Evidence map›Paper›PMID 41291168›Full record

ArticleInternal and emergency medicine2025

Clinical impact of a cardiothoracic ultrasound protocol in patients with ST-segment elevation myocardial infarction: the focused assessment in STEMI (FASTEMI) protocol.

Andre Barcellos Amon, Guilherme Pinheiro Machado, Guilherme Heiden Telo, Marina Petersen Saadi, Wagner Tadeu Azeredo Azevedo, Antônia Martins, Marina Nassif, Gustavo Neves de Araújo, Fernando Luís Scolari, Anderson Donelli da Silveira and 4 more

Abstract read
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In one paragraph

Article in Internal and emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Andre Barcellos AmonCardiology Department, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil. andreamon@hotmail.com.br.ORCID http://orcid.org/0009-0001-7116-6193
Guilherme Pinheiro MachadoCardiology Department, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.ORCID http://orcid.org/0000-0002-5514-2562
Guilherme Heiden TeloCardiology Department, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.ORCID http://orcid.org/0009-0005-2414-9453
Marina Petersen SaadiCardiology Department, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.ORCID http://orcid.org/0000-0001-6409-2109
Wagner Tadeu Azeredo AzevedoFaculty of Medicine, Federal University of Rio Grande Do Sul, Porto Alegre, Brazil.ORCID http://orcid.org/0000-0002-3771-2154
Antônia MartinsFaculty of Medicine, Federal University of Rio Grande Do Sul, Porto Alegre, Brazil.ORCID http://orcid.org/0000-0001-9222-8480
Marina NassifFaculty of Medicine, Federal University of Rio Grande Do Sul, Porto Alegre, Brazil.ORCID http://orcid.org/0009-0006-3334-7336
Gustavo Neves de AraújoCardiology Department, Instituto de Cardiologia de Santa Catarina, São José, Brazil.ORCID http://orcid.org/0000-0002-1989-1670
Fernando Luís ScolariCardiology Department, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.ORCID http://orcid.org/0000-0003-2150-6337
Anderson Donelli da SilveiraCardiology Department, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.ORCID http://orcid.org/0000-0002-0327-3392
Mir Babar BasirDivision of Cardiology, Henry Ford Hospital, Detroit, USA.ORCID http://orcid.org/0000-0003-3486-6753
Hatem Soliman-AboumarieDepartment of Cardiothoracic Anaethesia and Intensive Care, Harefield Hospital, Royal Brompton and Harefield Hospitals. King's College London, London, UK.ORCID http://orcid.org/0000-0002-3254-6820
Marco Vugman WainsteinCardiology Department, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.ORCID http://orcid.org/0000-0002-7284-1453
Rodrigo Vugman WainsteinCardiology Department, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.ORCID http://orcid.org/0000-0001-7596-2827

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ST-segment elevation myocardial infarction (STEMI) remains a condition with high morbidity despite advancements in treatment. Physical examination for heart failure and identification of mechanical complications can be inconsistent. Point-of-care ultrasound (POCUS) has proven valuable in acute cardiovascular care. We developed the Focused Assessment in STEMI (FASTEMI) protocol to enhance early evaluation, identify complications, and guide management. This single-center prospective cohort study included patients with presumed STEMI between June 2023 and June 2024. The FASTEMI protocol was performed upon admission and comprised lung ultrasound to assess congestion, and cardiac ultrasound to evaluate ventricular function, detect mechanical complications, measure left-ventricular outflow tract velocity-time integral, and assess the inferior vena cava. A total of 214 patients had a confirmed diagnosis of STEMI, whereas 17 were diagnosed with other conditions. FASTEMI altered diagnosis or management in 33 cases (14%) (CI 95% = 11.2 - 20.9). Identification of left ventricular (OR 1.26, 95% CI = 1.11-1.43; p < 0.001), right ventricular (OR 1.3, 95% CI = 1.04-1.75; p < 0.001), and biventricular dysfunction (OR 1.96, 95% CI 1.14-3.38; p < 0.001) were associated with in-hospital mortality. A normal FASTEMI exam had a 97% negative predictive value for mortality and did not delay door-to-balloon time. FASTEMI enhances early diagnosis, risk stratification, and management of STEMI. It enables rapid identification of complications, optimizes individualized treatment, and provides prognostic information without prolonging door-to-balloon time. Its feasibility supports its role as an adjunctive bedside tool.

Indexed as

EchocardiographyLung ultrasoundMortalityMyocardial infarctionPoint-of-care ultrasoundRisk stratification

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.