Evidence map›Paper›PMID 41291154›Full record

Observational studySupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

Distinctive trajectories of symptom burden, activities of daily living, and self-efficacy among patients with advanced cancer receiving care in an acute palliative care unit: a pilot longitudinal study.

Akihito Yanai, Ken Kondo, Takahiro Otsuka, Lisa Sato, Akiko Yanai, Hina Yoshizawa, Shiro Koizuka, Bumsuk Lee

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Akihito YanaiDoctoral Program, Graduate School of Health Sciences, Gunma University, Maebashi, Japan.
Ken KondoDepartment of Occupational Therapy, Faculty of Rehabilitation, Gunma Paz University, Takasaki, Japan.
Takahiro OtsukaDepartment of Rehabilitation, Gunma Rehabilitation Hospital, Nakanojo, Japan.
Lisa SatoDoctoral Program, Graduate School of Health Sciences, Gunma University, Maebashi, Japan.
Akiko YanaiDepartment of Occupational Therapy, Faculty of Rehabilitation, Gunma University of Health and Welfare, Maebashi, Japan.
Hina YoshizawaDepartment of Rehabilitation, Uchida Hospital, Numata, Japan.
Shiro KoizukaDivision of Palliative Care, Gunma Prefectural Cancer Center, Ota, Japan.
Bumsuk LeeGraduate School of Health Sciences, Gunma University, Maebashi, Japan. leebumsuk@gunma-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePatients with advanced cancer experience progressive deterioration in symptom burden, activities of daily living (ADLs), and self-efficacy as they approach the end of life. This pilot longitudinal study aimed to examine the trajectories of these indicators in a palliative care setting and to identify factors associated with survival time.

methodsWe conducted a prospective observational study of 70 patients with advanced cancer admitted to an acute palliative care unit (APCU) between November 2019 and March 2022. Outcomes included symptom burden, ADLs, and self-efficacy. Scores were reported by the patients or providers during admissions or ambulatory visits. Generalized linear mixed models and generalized additive models were used to analyze trajectories. Multiple regression was used to identify factors associated with time until death.

resultsA total of 227 assessments were performed. Symptom burden followed a U-shaped trajectory, with temporary relief followed by deterioration. ADLs and symptom coping efficacy (SCE) showed a cubic curve pattern, with a stable phase between 15 and 7 weeks. A delayed decline in SCE was observed after symptom worsening. SOB was the only significant predictor of weeks to death (standardized β = -0.251).

conclusionDistinctive trajectories were observed in symptom burden, ADLs, and self-efficacy, including a temporary stable phase and a delayed decline in SCE. These findings suggest that behavioral support in the APCU may help maintain patient functioning and guide timely care transitions.

Indexed as

Activities of Daily LivingNeoplasmsPalliative CareSelf EfficacyAdaptation, PsychologicalAgedAged, 80 and overFemaleHumansLongitudinal StudiesMaleMiddle AgedPilot ProjectsProspective StudiesSymptom BurdenADLAdvanced cancerObservational studySelf-efficacyShortness of breathSymptoms

Identifiers

PMID41291154

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.