Evidence map›Paper›PMID 41291093›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Mortality for pneumonia and risk of pneumonia in children with cerebral palsy treated with and without surgery.

Matti Ahonen, Ira Jeglinsky-Kankainen, Mika Gissler, Ilkka Helenius

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Matti AhonenDepartment of Paediatric Orthopaedics and Traumatology, Helsinki University Hospital, Helsinki, Finland. matti.ahonen@hus.fi.
Ira Jeglinsky-KankainenArcada University of Applied Sciences, Helsinki, Finland.
Mika GisslerFinnish Institute for Health and Welfare, Helsinki, Finland.
Ilkka HeleniusUniversity of Helsinki, Helsinki, Finland.

Funding

NordForsk 82866
6 · The paper itself

Abstract

purposeThe aim of this study was to compare the incidence of pneumonia and pneumonia-related mortality in children with cerebral palsy (CP) and scoliosis, with and without scoliosis surgery.

methodsNational registries were searched for individuals with CP and scoliosis born after 1987 with recordings between 1996 and 2021. Identified individuals were categorized according to scoliosis surgery and were compared for pneumonia incidence and pneumonia-related mortality. Multivariable Cox regression examined determinants of mortality.

resultsWe identified 474 children with CP and scoliosis, of these 236 children had not undergone surgery, while 238 had been operated. Both groups had similar rates of comorbidities. While there was no change in number of individuals with at least one hospitalization for pneumonia, there was significant reduction in cumulative pneumonia incidence from before to after surgery (175.5 vs. 121.5 hospitalizations per 1,000 years, p < 0.001), while incidence did not change in non-surgically treated patients (192.8 vs. 203.9, hospitalizations per 1,000 years, p = 0.35). During follow-up pneumonia-related mortality was significantly higher in the non-surgically treated group than in the surgically treated group (n = 21/236, 8.9% vs. n = 8/238, 3.3%, p = 0.008). After adjusting for covariates surgical patients had 87.5% reduction in risk of mortality to pneumonia compared with non-surgically treated patients (hazard ratio: 0.125, 95% confidence interval: 0.051-0.31, p < 0.001).

conclusionsThese results indicate that surgical treatment of scoliosis in children with CP associates to reduced incidence of pneumonia and pneumonia-related mortality.

Indexed as

Cerebral PalsyPneumoniaScoliosisAdolescentChildChild, PreschoolFemaleHumansIncidenceMaleRegistriesRisk FactorsCerebral palsyMortalityPneumoniaScoliosisSpinal fusion

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.