Evidence map›Paper›PMID 41291056›Full record

ArticleHeart and vessels2026

Geriatric nutritional risk index and C-reactive protein: prognostic impact in transcatheter aortic valve implantation.

Kayo Sugiyama, Masanobu Fujimoto, Wataru Suzuki, Kentaro Mukai, Masato Tochii, Hirotaka Watanuki, Tetsuya Amano, Katsuhiko Matsuyama

Abstract read
In one paragraph

Article in Heart and vessels, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kayo SugiyamaDepartment of Cardiac Surgery, Aichi Medical University Hospital, 1-1 Yazako Karimata, Nagakute, Aichi, 480-1195, Japan. kayotaro3@gmail.com.ORCID http://orcid.org/0000-0003-2384-6466
Masanobu FujimotoDepartment of Cardiology, Aichi Medical University Hospital, Nagakute, Japan.
Wataru SuzukiDepartment of Cardiology, Aichi Medical University Hospital, Nagakute, Japan.
Kentaro MukaiDepartment of Cardiology, Aichi Medical University Hospital, Nagakute, Japan.
Masato TochiiDepartment of Cardiac Surgery, Aichi Medical University Hospital, 1-1 Yazako Karimata, Nagakute, Aichi, 480-1195, Japan.
Hirotaka WatanukiDepartment of Cardiac Surgery, Aichi Medical University Hospital, 1-1 Yazako Karimata, Nagakute, Aichi, 480-1195, Japan.
Tetsuya AmanoDepartment of Cardiology, Aichi Medical University Hospital, Nagakute, Japan.
Katsuhiko MatsuyamaDepartment of Cardiac Surgery, Aichi Medical University Hospital, 1-1 Yazako Karimata, Nagakute, Aichi, 480-1195, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The impact of inflammatory and nutritional indices in patients undergoing transcatheter aortic valve implantation (TAVI) remains controversial. Therefore, we aimed to analyze the prognostic impact of Geriatric Nutritional Risk Index (GNRI) and C-reactive protein (CRP) in these patients. We included 122 patients who underwent elective TAVI for aortic valve stenosis (AS) between April 2017 and May 2023. The primary outcome was all-cause mortality, and secondary outcomes were major adverse cerebral/cardiovascular events (MACCEs). Patients with a low GNRI, high CRP levels, and a combination of a low GNRI and high CRP levels exhibited significantly high all-cause mortality. The GNRI and CRP levels alone were significantly associated with late mortality in the univariate analysis; however, this trend was absent in the multivariate analysis. The combination of a low GNRI and high CRP levels was significantly associated with late mortality in the univariate and multivariate analyses. The GNRIs at 6 months showed no significant changes, and the low GNRI in patients before surgery persisted after TAVI. There was no association between low GNRI after TAVI and late mortality or MACCE. The combination of malnutrition (indicated by a low GNRI) and inflammation (indicated by high CRP levels) may be a risk factor for long-term mortality in patients undergoing TAVI for AS.

Indexed as

Aortic Valve StenosisC-Reactive ProteinGeriatric AssessmentMalnutritionNutritional StatusNutrition AssessmentTranscatheter Aortic Valve ReplacementAgedAged, 80 and overBiomarkersFemaleFollow-Up StudiesHumansMalePrognosisRetrospective StudiesBiomarkersC-Reactive ProteinAortic valve stenosisC-reactive proteinGeriatric Nutritional Risk IndexTranscatheter aortic valve implantation

Identifiers

PMID41291056
PMCPMC13076512

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.