Evidence map›Paper›PMID 41291016›Full record

ArticleScientific reports2025

Caesalpinia sappan is a potent source of multi-functional bioactive compounds.

Zhishu Li, Qiongqiong Yang, Peiwen Wang

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhishu LiDepartment of Biology, College of Science, Shantou University, Shantou, 515063, Guangdong, China.
Qiongqiong YangCollege of Light Industry and Food Engineering, Guangxi University, 100 Daxue Road, Nanning, 530004, Guangxi, China. qiongqiongyang@stu.edu.cn.
Peiwen WangGuangdong Jiangmen Chinese Medicine College, Jiangmen, 529099, Guangdong, China. ridywpw@163.com.

Funding

Li Ka Shing Foundation STU-GTIIT Joint-research Grant 2025LKSFG06National Natural Science Foundation of China 32302280Youth S&T Talent Support Programme of Guangdong Provincial Association for Science and Technology SKXRC2025037
6 · The paper itself

Abstract

Traditional Chinese medicinal (TCM) plants have become an important source for screening natural bioactive compounds. This study aimed to compare the phenolic profiles, and antioxidant, antiproliferative, and antibacterial activities of sixteen TCM extracts, to evaluate their effects on intracellular reactive oxygen species (ROS), and to characterize the major bioactive constituents in the most promising plants. Wide ranges of variation were found in methanolic plant extracts for total phenolics (31.3-1247 mg gallic acid equivalent (GAE)/100 g dry extract (DE)), total flavonoids (1.12-346 mg catechin equivalent (CE)/100 g DE), antioxidant activities, antiproliferative effects against four cancer cell lines with IC

Indexed as

CaesalpiniaPlant ExtractsAnti-Bacterial AgentsAntineoplastic Agents, PhytogenicAntioxidantsCell Line, TumorCell ProliferationFlavonoidsHumansMicrobial Sensitivity TestsPhenolsReactive Oxygen SpeciesAnti-Bacterial AgentsAntineoplastic Agents, PhytogenicAntioxidantsFlavonoidsPhenolsPlant ExtractsReactive Oxygen SpeciesBiological activityCaesalpinia sappanHeartwoodPhytochemicalsROS

Identifiers

PMID41291016
PMCPMC12749679

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.