Evidence map›Paper›PMID 41290964›Full record

ArticleScientific reports2025

Association of the existence of CRISPR-Cas system and antimicrobial resistance in multi-drug resistant Klebsiella pneumoniae in Egypt.

Nagwan Galal El Menofy, Aya Nassef Payoumi, Mohamed A Eissa, Amany El-Sharif

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nagwan Galal El MenofyMicrobiology and Immunology Department, Faculty of Pharmacy, Al- Azhar University, Cairo, 11765, Egypt. nagwan.elmenofy@azhar.edu.eg.
Aya Nassef PayoumiMicrobiology and Immunology Department, Faculty of Pharmacy, Al- Azhar University, Cairo, 11765, Egypt.
Mohamed A EissaBiotechnology Department, Faculty of Agriculture, Al-Azhar University, Cairo, 11754, Egypt.
Amany El-SharifMicrobiology and Immunology Department, Faculty of Pharmacy, Al- Azhar University, Cairo, 11765, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The CRISPR-Cas systems are supposed to be associated with antibiotic susceptibility. Klebsiella pneumoniae (K. pneumoniae) is a major multidrug-resistant (MDR) pathogen that may cause severe infections. This study aimed to detect the antimicrobial resistance (AMR) of K. pneumoniae isolates in addition to determine the association between the existence of CRISPR-Cas systems and the presence of AMR in Egypt. The antibiotic susceptibility patterns of 100 K. pneumoniae isolates were determined using the Kirby Bauer disc diffusion and broth microdilution methods. The frequency of carbapenem resistance encoding genes (bla

Indexed as

Anti-Bacterial AgentsCRISPR-Cas SystemsDrug Resistance, Multiple, BacterialKlebsiella InfectionsKlebsiella pneumoniaeBacterial Proteinsbeta-LactamasesColistinEgyptHumansMicrobial Sensitivity TestsAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesColistinAssociationCarbapenem resistanceColistinCRISPR/CasK. pneumoniaeMultidrug resistant

Identifiers

PMID41290964
PMCPMC12647879

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.