Evidence map›Paper›PMID 41290963›Full record

ArticleScientific reports2025

Different larval habitats and insecticide resistance frequency of Anopheles sinensis in Ganghwagun, Incheon, South Korea.

Tae-Hui Eom, Hyun-Young Lee, Hyelee Hong, Eunho Lee, Jiseok Lee, Jong Hyun Eun, Sunhae Seo, Yuna Goh, Eun Lee, Seon-Ju Yeo

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Tae-Hui Eom *Department of Tropical Medicine and Parasitology, Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, 03080, South Korea.
Hyun-Young Lee *Department of Tropical Medicine and Parasitology, Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, 03080, South Korea.
Hyelee Hong *Department of Tropical Medicine and Parasitology, Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, 03080, South Korea.
Eunho LeeDepartment of Tropical Medicine and Parasitology, Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, 03080, South Korea.
Jiseok LeeDepartment of Medicine, College of Medicine, Seoul National University, Seoul, 03080, Republic of Korea.
Jong Hyun EunDepartment of Tropical Medicine and Parasitology, Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, 03080, South Korea.
Sunhae SeoDepartment of Tropical Medicine and Parasitology, Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, 03080, South Korea.
Yuna GohDepartment of Tropical Medicine and Parasitology, Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, 03080, South Korea.
Eun LeeInstitute of Endemic Diseases, Seoul National University Medical Research Center, Seoul, 03080, South Korea.
Seon-Ju YeoDepartment of Tropical Medicine and Parasitology, Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, 03080, South Korea. yeosj@snu.ac.kr.

Funding

Korea Health Industry Development Institute (RS-2024-00507732National Research Foundation of Korea 2024M3A9H5043148
6 · The paper itself

Abstract

Monitoring the ecology and insecticide resistance of Anopheles mosquitoes, which transmit malaria, is important for developing effective malaria control strategies. This study characterized the present larval breeding habitats of Anopheles mosquitoes in South Korea; additionally, we investigated the frequency of insecticide resistance in Anopheles in the Ganghwagun, Gyeonggi-do province, near the demilitarized zone (DMZ), of South Korea. While larvae of An. sineroides and An. lindesayi were found near forests in Naega-myeon and Kukhwa-ri, respectively, An. sinensis larvae were predominantly found in irrigation canal near rice fields in Seonhaeng-ri, alongside An. belenrae. Seven genotypes of knockdown resistant (kdr) allele in the voltage-gated sodium channel of An. sinensis were introduced, revealing a new kdr genotype. Notably, almost all of An. sinensis captured in this study was shown mutant genotypes with homozygous or heterozygous resistant alleles of acetylcholinesterase (ace-1). Moreover, the predominant presence of mosquitoes harboring mutations in more than one insecticidal target was observed in An. sinensis. In addition, An. belenrae was identified to possess kdr and ace-1 mutation. Taken together, our findings revealed the multiple insecticide resistance of An. sinensis, with larval habitat near the DMZ of South Korea, 2024.

Indexed as

AnophelesEcosystemInsecticide ResistanceAcetylcholinesteraseAllelesAnimalsGenotypeInsecticidesLarvaMosquito VectorsMutationRepublic of KoreaAcetylcholinesteraseInsecticidesAcetylcholinesterase (ace-1) alleleAnopheles sinensisKnockdown resistant (kdr) alleleLarvae habitatNew kdr genotypeSouth Korea

Identifiers

PMID41290963
PMCPMC12748694

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