Evidence map›Paper›PMID 41290885›Full record

ArticleScientific reports2025

Design, synthesis, and antifungal activity of 14-aryloxy/amide substituted andrographolide derivatives.

Zhuyun Liu, Shanshan Yang, Jierui Ma, Yunying Sha, Yuyan Zhou, Zhuqing Liu, Lizhong Wang

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhuyun LiuSchool of Intelligent Pharmaceutical Manufacturing & New Chemical Engineering Materials, Taizhou Polytechnic College, Taizhou, 225300, Jiangsu, PR China. llzzyy23@163.com.
Shanshan YangSchool of Intelligent Pharmaceutical Manufacturing & New Chemical Engineering Materials, Taizhou Polytechnic College, Taizhou, 225300, Jiangsu, PR China.
Jierui MaSchool of Intelligent Pharmaceutical Manufacturing & New Chemical Engineering Materials, Taizhou Polytechnic College, Taizhou, 225300, Jiangsu, PR China.
Yunying ShaSchool of Intelligent Pharmaceutical Manufacturing & New Chemical Engineering Materials, Taizhou Polytechnic College, Taizhou, 225300, Jiangsu, PR China.
Yuyan ZhouSchool of Intelligent Pharmaceutical Manufacturing & New Chemical Engineering Materials, Taizhou Polytechnic College, Taizhou, 225300, Jiangsu, PR China.
Zhuqing LiuDepartment of Intensive Care Medicine, Taizhou People's Hospital, Taizhou, Jiangsu, 225300, PR China. 3873417558@qq.com.
Lizhong WangSchool of Intelligent Pharmaceutical Manufacturing & New Chemical Engineering Materials, Taizhou Polytechnic College, Taizhou, 225300, Jiangsu, PR China.

Funding

2024 College Students' Innovation and Entrepreneurship Cultivation Plan Project TZY20240242024 Taizhou Vocational Education Federation (Taizhou Vocational Education Group) - Taizhou Polytechnic College Joint Research Project NO. 2024BZD02Research Project of Basic Science (Natural Science) in Colleges and Universities of Jiangsu Province NO. 23KJD350004
6 · The paper itself

Abstract

In order to find more compounds with antifungal activities, a series of new compounds were designed and synthesized using the natural product of diterpenoid lactones, andrographolide, as the parent nucleus. Target compounds were identified by

Indexed as

Antifungal AgentsDiterpenesDrug DesignFungiMicrobial Sensitivity TestsMolecular StructureStructure-Activity RelationshipandrographolideAntifungal AgentsDiterpenes

Identifiers

PMID41290885
PMCPMC12647904

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.