Evidence map›Paper›PMID 41290791›Full record

ArticleScientific reports2025

Magnetic hyperthermia using iron oxide nanoparticles via LDDS suppressed lymph node and lung metastasis in a mouse model.

Akihiro Kuwahata, Ariunbuyan Sukhbaatar, Akihiro Shikano, Loi Tonthat, Takayuki Kagami, Riku Shinohara, Shiro Mori, Shin Yabukami, Tetsuya Kodama

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Akihiro KuwahataGraduate School of Engineering, Tohoku University, 6-6-05, Aramaki Aza-Aoba, Sendai, 980-8579, Japan.
Ariunbuyan SukhbaatarGraduate School of Biomedical Engineering, Tohoku University, 6-6-12, Aramaki Aza-Aoba, Sendai, 980-8579, Japan.
Akihiro ShikanoGraduate School of Engineering, Tohoku University, 6-6-05, Aramaki Aza-Aoba, Sendai, 980-8579, Japan.
Loi TonthatGraduate School of Engineering, Tohoku University, 6-6-05, Aramaki Aza-Aoba, Sendai, 980-8579, Japan.
Takayuki KagamiGraduate School of Biomedical Engineering, Tohoku University, 6-6-12, Aramaki Aza-Aoba, Sendai, 980-8579, Japan.
Riku ShinoharaGraduate School of Engineering, Tohoku University, 6-6-05, Aramaki Aza-Aoba, Sendai, 980-8579, Japan.
Shiro MoriGraduate School of Biomedical Engineering, Tohoku University, 6-6-12, Aramaki Aza-Aoba, Sendai, 980-8579, Japan.
Shin YabukamiGraduate School of Engineering, Tohoku University, 6-6-05, Aramaki Aza-Aoba, Sendai, 980-8579, Japan. shin.yabukami.e7@tohoku.ac.jp.
Tetsuya KodamaGraduate School of Engineering, Tohoku University, 6-6-05, Aramaki Aza-Aoba, Sendai, 980-8579, Japan. kodama@tohoku.ac.jp.

Funding

AMED (Japan Agency for Medical Research and Development) 23he0422030j0001, 24he0422030j0002JSPS Kakenhi grant numbers 20K20161, 22K18203JSPS Kakenhi grant numbers 21K18319, 23H00543JSPS KAKENHI grant numbers JP23H03721, JP23K28410
6 · The paper itself

Abstract

Lymph node (LN) metastasis remains a critical determinant of cancer progression and prognosis, yet surgical interventions result in adverse effects. In this preclinical study, we investigated a minimally invasive therapeutic approach combining magnetic hyperthermia (MH) with a lymphatic drug delivery system (LDDS) using iron oxide nanoparticles (Resovist

Indexed as

Hyperthermia, InducedLung NeoplasmsLymphatic MetastasisMagnetic Iron Oxide NanoparticlesAnimalsCell Line, TumorDisease Models, AnimalDrug Delivery SystemsFemaleLymph NodesMiceIron oxide nanoparticlesLymphatic drug delivery systemLymph node metastasisMagnetic hyperthermiaResovist®

Identifiers

PMID41290791
PMCPMC12647774

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.