Evidence map›Paper›PMID 41290733›Full record

ArticleScientific reports2025

The choline chloride/hydroquinone carboxylic acid-based DES as a novel catalyst for the green synthesis of dihydrochromeno[4,3-d]pyrimidinediones.

Zahra Jahanian, Davood Habibi, Arezo Monem, Elnaz Chegeni

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zahra JahanianFaculty of Chemistry and Petroleum Sciences, Department of Organic Chemistry, Bu-Ali Sina University, Hamedan, Iran.
Davood HabibiFaculty of Chemistry and Petroleum Sciences, Department of Organic Chemistry, Bu-Ali Sina University, Hamedan, Iran. davood.habibi@gmail.com.
Arezo MonemFaculty of Chemistry and Petroleum Sciences, Department of Organic Chemistry, Bu-Ali Sina University, Hamedan, Iran.
Elnaz ChegeniFaculty of Chemistry and Petroleum Sciences, Department of Organic Chemistry, Bu-Ali Sina University, Hamedan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel deep eutectic solvent (ChCl/HCA-DES) was prepared by combining two moles of choline chloride (ChCl) with one mole of hydroquinone carboxylic acid (HCA), based on the results from the eutectic point phase diagram, and characterized by FT-IR, ¹H NMR, TGA/DTA, densitometry, viscometry, and refractive index analyses. Then, it was subsequently employed as an efficient, environmentally friendly and sustainable catalytic system for the synthesis of dihydrochromeno [4,3-d]pyrimidinediones via the three-component condensation reaction of 4-hydroxycoumarin, aromatic aldehydes, and urea at 60 °C under solvent-free conditions. This green protocol offers high yields, short reaction times, and catalyst reusability.

Indexed as

Choline chlorideHomogeneous catalysisHydroquinone carboxylic acidMulticomponent reactionsNatural deep eutectic solvent

Identifiers

PMID41290733
PMCPMC12647802

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.