Evidence map›Paper›PMID 41290682›Full record

ArticleScientific data2025

Genome assembly and structural variations of Guyuan cattle.

Shuang Liu, Huixuan Yan, Yuan Liu, Fen Li, Xiaoting Xia, Dawei Wei, Bei Cai, Chuzhao Lei, Ningbo Chen, Yun Ma

Abstract readDataset
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shuang Liu *Key Laboratory of Molecular Cell Breeding of Ruminants in Ningxia Hui Autonomous Region, College of Animal Science and Technology, Ningxia University, Yinchuan, 750021, China.
Huixuan Yan *Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China.
Yuan Liu *Key Laboratory of Molecular Cell Breeding of Ruminants in Ningxia Hui Autonomous Region, College of Animal Science and Technology, Ningxia University, Yinchuan, 750021, China.
Fen LiKey Laboratory of Molecular Cell Breeding of Ruminants in Ningxia Hui Autonomous Region, College of Animal Science and Technology, Ningxia University, Yinchuan, 750021, China.
Xiaoting XiaKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China.
Dawei WeiKey Laboratory of Molecular Cell Breeding of Ruminants in Ningxia Hui Autonomous Region, College of Animal Science and Technology, Ningxia University, Yinchuan, 750021, China.
Bei CaiKey Laboratory of Molecular Cell Breeding of Ruminants in Ningxia Hui Autonomous Region, College of Animal Science and Technology, Ningxia University, Yinchuan, 750021, China.
Chuzhao LeiKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China. leichuzhao1118@nwafu.edu.cn.
Ningbo ChenKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China. ningbochen@nwafu.edu.cn.
Yun MaKey Laboratory of Molecular Cell Breeding of Ruminants in Ningxia Hui Autonomous Region, College of Animal Science and Technology, Ningxia University, Yinchuan, 750021, China. mayun@nxu.edu.cn.ORCID 0000-0002-8018-545X

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32472871National Natural Science Foundation of China (National Science Foundation of China) U22A20506
6 · The paper itself

Abstract

Guyuan cattle, a transitional breed between northern and central Chinese cattle, are known for their climbing ability and disease resistance. However, the genomic resources of indigenous Chinese cattle breeds, including Guyuan cattle, remain largely unexplored. We first assembled the Guyuan cattle genome, named Guyuan_Btau_1.0, using PacBio HiFi sequencing. Guyuan_Btau_1.0, with a total size of 2.86 Gb, was anchored to 30 chromosomes (29 autosomes plus one X), achieving a contig N50 of 85.27 Mb and a scaffold N50 of 107.67 Mb. Additionally, we sequenced the genomes of 10 Guyuan cattle using Oxford Nanopore sequencing, which detected 65,273 structural variations (SVs) with lengths of 40.37 Mb and 4,849 shared SVs with lengths of 3.15 Mb. Across the shared SVs, we identified, visualized, and validated a 1,290 bp deletion in the second intron of IGF2BP2 gene in the genomes of 10 Guyuan cattle relative to ARS-UCD1.2. Overall, this study enriches the genetic resource database of indigenous Chinese cattle and provides new foundational data for the breeding and genetic improvement of Guyuan cattle.

Indexed as

GenomeGenomic Structural VariationAnimalsCattleChina

Identifiers

PMID41290682
PMCPMC12647171

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.