Evidence map›Paper›PMID 41290396›Full record

ArticleInfluenza and other respiratory viruses2025

COVID-19 Vaccine Effectiveness Against Hospitalization in Older Adults, VEBIS Hospital Network, Europe, September 2024-May 2025.

Madelyn Rojas-Castro, Nuno Verdasca, Susana Monge, Laurane De Mot, Camino Trobajo-Sanmartín, Róisín Duffy, Gergő Túri, Monika Kuliese, Ralf Duerrwald, Maria-Louise Borg and 27 more

Abstract readMulticenter Study
In one paragraph

Article in Influenza and other respiratory viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

Madelyn Rojas-CastroEpiconcept, Paris, France.ORCID https://orcid.org/0000-0001-7006-7946
Nuno VerdascaInfectious Diseases Department, National Health Institute Doutor Ricardo Jorge, Lisbon, Portugal.ORCID https://orcid.org/0000-0002-4673-5411
Susana MongeNational Centre of Epidemiology, CIBERINFEC, Institute of Health Carlos III, Madrid, Spain.ORCID https://orcid.org/0000-0003-1412-3012
Laurane De MotScientific Directorate of Epidemiology of Infectious Diseases, Sciensano, Brussels, Belgium.ORCID https://orcid.org/0000-0003-3821-1957
Camino Trobajo-SanmartínInstituto de Salud Pública de Navarra - IdiSNA - CIBERESP, Pamplona, Spain.ORCID https://orcid.org/0000-0001-5105-252X
Róisín DuffyHealth Service Executive-Health Protection Surveillance Centre (HPSC), Dublin, Ireland.ORCID https://orcid.org/0009-0001-7169-9109
Gergő TúriNational Laboratory for Health Security, Epidemiology and Surveillance Centre, Semmelweis University, Budapest, Hungary.ORCID https://orcid.org/0000-0003-3465-8321
Monika KulieseDepartment of Infectious Diseases, Lithuanian University of Health Sciences, Kaunas, Lithuania.ORCID https://orcid.org/0000-0002-4601-4585
Ralf DuerrwaldNational Reference Centre for Influenza, Robert Koch Institute, Berlin, Germany.ORCID https://orcid.org/0000-0002-3432-0438
Maria-Louise BorgInfectious Disease Prevention and Control Unit (IDCU), Msida, Malta.ORCID https://orcid.org/0000-0001-8961-9413
Odette PopoviciNational Institute of Public Health (INSP/NIPH) - National Centre for Surveillance and Control of Communicable Diseases, Bucharest, Romania.ORCID https://orcid.org/0000-0003-4157-2622
Verónica GomezDepartment of Epidemiology, National Institute of Health Doctor Ricardo Jorge, Lisbon, Portugal.ORCID https://orcid.org/0000-0003-0485-0005
Zvjezdana Lovrić MakarićDivison for Epidemiology of Communicable Diseases, Croatian Institute of Public Health, Zagreb, Croatia.ORCID https://orcid.org/0000-0003-4285-2116
Odile LaunayINSERM CIC 1417, F-CRIN, I-REIVAC Network, Assistance Publique-Hôpitaux de Paris, Hôpital Cochin Paris, Paris, France.ORCID https://orcid.org/0000-0003-3242-7247
Diogo F P MarquesEpiconcept, Paris, France.ORCID https://orcid.org/0000-0002-2556-0923
Francisco PozoNational Centre of Microbiology, CIBERESP, Institute of Health Carlos III, Madrid, Spain.ORCID https://orcid.org/0000-0003-1828-733X
Arne WitdouckDepartment of Internal Medicine and Infectious Diseases, Universitair Ziekenhuis Brussel, Brussels, Belgium.ORCID https://orcid.org/0009-0007-6699-1010
Iván Martínez-BazInstituto de Salud Pública de Navarra - IdiSNA - CIBERESP, Pamplona, Spain.ORCID https://orcid.org/0000-0002-3405-2277
Margaret FitzgeraldHealth Service Executive-Health Protection Surveillance Centre (HPSC), Dublin, Ireland.ORCID https://orcid.org/0000-0002-4535-0966
Beatrix OrosziNational Laboratory for Health Security, Epidemiology and Surveillance Centre, Semmelweis University, Budapest, Hungary.ORCID https://orcid.org/0000-0001-8915-0336
Ligita JančorienėClinic of Infectious Diseases and Dermatovenerology, Institute of Clinical Medicine, Medical Faculty, Vilnius University, Vilnius, Lithuania.ORCID https://orcid.org/0000-0001-6488-6312
Silke BudaNational Reference Centre for Influenza, Robert Koch Institute, Berlin, Germany.ORCID https://orcid.org/0000-0003-3448-3357
Ausra DziugyteInfectious Disease Prevention and Control Unit (IDCU), Msida, Malta.ORCID https://orcid.org/0000-0003-0486-8491
Mihaela LazărNational Institute of Research & Development for Microbiology & Immunology (INCDMM) "Cantacuzino", Bucharest, Romania.ORCID https://orcid.org/0000-0002-8226-6026
Ausenda MachadoDepartment of Epidemiology, National Institute of Health Doctor Ricardo Jorge, Lisbon, Portugal.ORCID https://orcid.org/0000-0002-1849-1499
Irena TabainDepartment for Direct Diagnostic Virology, Croatian Institute of Public Health, Zagreb, Croatia.ORCID https://orcid.org/0000-0002-2518-522X
Liem Binh Luong NguyenINSERM CIC 1417, F-CRIN, I-REIVAC Network, Assistance Publique-Hôpitaux de Paris, Hôpital Cochin Paris, Paris, France.ORCID https://orcid.org/0000-0002-5235-0868
Eva Rivas WagnerUnida de Vigilancia Epidemiológica de la Dirección General de Salud Pública, Servicio Canario de la Salud, Islas Canarias, Spain.ORCID https://orcid.org/0000-0002-9925-0784
François DufrasneNational Reference Center for Respiratory Pathogens, Belgium, Sciensano, Brussels, Belgium.ORCID https://orcid.org/0000-0001-6288-7936
Jesús CastillaInstituto de Salud Pública de Navarra - IdiSNA - CIBERESP, Pamplona, Spain.ORCID https://orcid.org/0000-0002-6396-7265
Lisa DomeganHealth Service Executive-Health Protection Surveillance Centre (HPSC), Dublin, Ireland.ORCID https://orcid.org/0000-0002-7483-6703
Viktória VelkeyNational Laboratory for Health Security, Epidemiology and Surveillance Centre, Semmelweis University, Budapest, Hungary.
Fausta MajauskaiteClinic of Infectious Diseases and Dermatovenerology, Institute of Clinical Medicine, Medical Faculty, Vilnius University, Vilnius, Lithuania.ORCID https://orcid.org/0009-0007-4307-9547
Carolin HackmannDepartment of Infectious Disease Epidemiology, Respiratory Infections Unit, Robert Koch Institute, Berlin, Germany.ORCID https://orcid.org/0000-0001-8788-3632
Nathalie NicolayEuropean Centre for Disease Prevention and Control, Stockholm, Sweden.
Sabrina BacciEuropean Centre for Disease Prevention and Control, Stockholm, Sweden.
Angela M C RoseEpiconcept, Paris, France.ORCID https://orcid.org/0000-0002-2493-8082

Funding

European Centre for Disease Prevention and Control ECDC/2021/016 (EU-H)
6 · The paper itself

Abstract

We estimated COVID-19 vaccine effectiveness (VE) against PCR-confirmed SARS-CoV-2 hospitalization in patients ≥ 60 years with severe acute respiratory infection, using a multicenter, test-negative, case-control study across seven sites in six European countries between September 2024 and May 2025. We included 352 cases (115 vaccinated; 33%) and 9980 controls (5024 vaccinated; 50%). VE was 42% (95% CI: 15; 61) 14-59 days post-vaccination, 32% (95% CI: -1; 54) at 60-119 days, and 36% (95% CI: 2; 60) at 120-179 days, and no effect thereafter. Among adults aged 60-79 and ≥ 80 years, we observed moderate VE against COVID-19 hospitalization for up to 2 and 4 months, respectively.

Indexed as

COVID-19COVID-19 VaccinesHospitalizationVaccine EfficacyAgedAged, 80 and overCase-Control StudiesEuropeFemaleHumansMaleMiddle AgedSARS-CoV-2VaccinationCOVID-19 Vaccinescase–control studyelderlysevere acute respiratory infection (SARI)test‐negative designvaccine effectiveness

Identifiers

PMID41290396
PMCPMC12646827

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.