Evidence map›Paper›PMID 41289418›Full record

ArticlePlastic and reconstructive surgery2026

Hospital Setting Impact on Breast Cancer-Related Lymphedema and Quality of Life after Immediate Lymphatic Reconstruction.

Abbas M Hassan, John P Hajj, John P Lewis, Shahnur Ahmed, Carla S Fisher, Rachel M Danforth, R Jason VonDerHaar, Ravinder Bamba, Mary E Lester, Aladdin H Hassanein

Abstract readMulticenter StudyComparative Study
In one paragraph

Article in Plastic and reconstructive surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Abbas M HassanFrom the Divisions of Plastic Surgery.
John P HajjFrom the Divisions of Plastic Surgery.
John P LewisFrom the Divisions of Plastic Surgery.
Shahnur AhmedFrom the Divisions of Plastic Surgery.
Carla S FisherBreast Surgery, Indiana University School of Medicine.
Rachel M DanforthFrom the Divisions of Plastic Surgery.
R Jason VonDerHaarFrom the Divisions of Plastic Surgery.
Ravinder BambaFrom the Divisions of Plastic Surgery.
Mary E LesterFrom the Divisions of Plastic Surgery.
Aladdin H HassaneinFrom the Divisions of Plastic Surgery.

Funding

Novel Mechanisms in the Resolution of Post-Surgical LymphedemaK08HL167164 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI Aladdin Hasan Hassanein · 2023 to 2026
$595k
NHLBI NIH HHS K08 HL167164
6 · The paper itself

Abstract

backgroundHospital setting may influence surgical outcomes, but its impact on immediate lymphatic reconstruction (ILR) for preventing breast cancer-related lymphedema (BCRL) after axillary lymph node dissection is unknown. This study assesses BCRL incidence and related outcomes after ILR comparing academic and community hospitals within a multihospital network.

methodsThe authors retrospectively studied consecutive patients who underwent ILR after axillary lymph node dissection between 2017 and 2024 across 6 hospitals. Hospitals were categorized as academic or community-based. The primary outcome (BCRL incidence) and secondary outcomes (complications and patient-reported outcomes [LYMPH-Q]) were compared using multivariable regression models adjusting for patient and treatment factors.

resultsThe authors identified 172 patients with a mean age 50.9 ± 11.6 years, body mass index of 29.5 ± 6.9 kg/m 2 , and follow-up time of 23.1 ± 15.2 months. ILR occurred at academic hospitals in 88 patients (51.2%) and at community hospitals in 84 patients (48.8%). BCRL incidence was comparable between academic (6.8%) and community (7.1%) settings ( P = 0.933). In multivariable regression, hospital setting was not significantly associated with the odds of developing BCRL (odds ratio [OR], 0.80; P = 0.730), surgical complications (OR, 1.21; P = 0.642), unplanned reoperation (OR, 1.43; P = 0.418), or LYMPH-Q Symptoms (β, -11.20; P = 0.063), Function (β, -4.9; P = 0.834), Appearance (β, -7.16; P = 0.413), or Psychological Well-Being (β, -5.25; P = 0.504) scales.

conclusionsILR demonstrated comparable outcomes for BCRL incidence, complications, and patient-reported quality of life between academic and community settings. These findings suggest that ILR can be successfully implemented beyond traditional academic centers with appropriate surgeon expertise and institutional support, potentially improving access to preventative lymphedema surgery.

Indexed as

Breast Cancer LymphedemaBreast NeoplasmsHospitals, CommunityLymphedemaLymph Node ExcisionPostoperative ComplicationsQuality of LifeAcademic Medical CentersAdultAxillaFemaleHumansIncidenceMastectomyMiddle AgedPatient Reported Outcome Measures

Identifiers

PMID41289418
PMCPMC13034129

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.