Evidence map›Paper›PMID 41289397›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Redox regulation of memory formation by Rrp1 in

Cheng-Tzu Hsu, Chun-Chao Chen, Yu-Ling Hung, Ya-Ting Yang, Yen-Hua Chiu, Sing-Shien Fong, Jung-Hsuan Yang, Zheng-Wen Wu, Jian-Wei Liou, Hsuan-Wen Lin and 3 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Redox regulation of memory formation by Rrp1 inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Cheng-Tzu HsuInstitute of Biotechnology and Department of Life Science, National Tsing-Hua University, Hsinchu 30013, Taiwan.ORCID 0009-0006-0280-4987
Chun-Chao ChenInstitute of Precision Medicine, College of Medicine, National Sun Yat-sen University, Kaohsiung 804201, Taiwan.
Yu-Ling HungInstitute of Biotechnology and Department of Life Science, National Tsing-Hua University, Hsinchu 30013, Taiwan.ORCID 0000-0002-1465-537X
Ya-Ting YangInstitute of Biotechnology and Department of Life Science, National Tsing-Hua University, Hsinchu 30013, Taiwan.
Yen-Hua ChiuInstitute of Biotechnology and Department of Life Science, National Tsing-Hua University, Hsinchu 30013, Taiwan.
Sing-Shien FongInstitute of Biotechnology and Department of Life Science, National Tsing-Hua University, Hsinchu 30013, Taiwan.
Jung-Hsuan YangInstitute of Biotechnology and Department of Life Science, National Tsing-Hua University, Hsinchu 30013, Taiwan.
Zheng-Wen WuInstitute of Biotechnology and Department of Life Science, National Tsing-Hua University, Hsinchu 30013, Taiwan.
Jian-Wei LiouInstitute of Biotechnology and Department of Life Science, National Tsing-Hua University, Hsinchu 30013, Taiwan.
Hsuan-Wen LinDepartment of Biomedical Science and Technology, College of Medicine, National Sun Yat-sen University, Kaohsiung 804201, Taiwan.
Kuan-Lin FengBrain Research Center, National Tsing Hua University, Hsinchu 30013, Taiwan.ORCID 0009-0007-0086-4000
Jia-Ling YangInstitute of Biotechnology and Department of Life Science, National Tsing-Hua University, Hsinchu 30013, Taiwan.
Ann-Shyn ChiangInstitute of Biotechnology and Department of Life Science, National Tsing-Hua University, Hsinchu 30013, Taiwan.ORCID 0000-0001-9668-7115

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long-term memory (LTM) formation requires precise gene regulation, yet the role of redox activity in this process remains poorly understood. Here, we identify

Indexed as

Drosophila melanogasterDrosophila ProteinsMemoryMemory, Long-TermAnimalsCalcium-Calmodulin-Dependent Protein Kinase Type 2DNA-(Apurinic or Apyrimidinic Site) LyaseDrosophilaHumansNeuronsOxidation-ReductionCalcium-Calmodulin-Dependent Protein Kinase Type 2DNA-(Apurinic or Apyrimidinic Site) LyaseDrosophila Proteinsapurinic/apyrimidinic endonuclease 1 (APE1)long-term memoryrecombination repair protein 1 (Rrp1)redox regulation

Identifiers

PMID41289397
PMCPMC12685121

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.