Trial reportPloS one2025
How weather affects cognitive and physical outcomes in older adults.
Trial report in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo ascertain whether, in comparison to the participants' expected abilities, the weather may cause abnormally poor cognitive or physical performance. Design Secondary analysis of a randomised controlled trial.
settingStudy conducted between May, 2008, and Feb, 2011 in 13 memory centres in France and Monaco.
participants1313 participants from the MAPT trial, a 5-year multicentre prevention trial, which included dementia-free individuals aged over 70 years. Participants presented subjective memory complaints, slow gait speed and/or an instrumental activity of daily living limitation.
main outcome measuresCognition was assessed using a composite cognitive Z-score (composed of digit symbol substitution test, free and cued selective reminding test, Mini-mental state, category fluency) and subjective memory complaints. Physical function was assessed using gait speed, the short physical performance battery (SPPB) and its components, and grip strength. Abnormally low scores were defined as an observed score that was lower than the individual's expected ability by at least the minimal clinically important difference.
resultsHigher outdoor temperature was associated with a significantly increased risk of abnormally low gait speed or SPPB (respectively OR 1.13 95% CI (1.04, 1.22) and OR 1.15 95% CI (1.03, 1.29) for 10 degrees Celsius), but did not significantly increase the risk of abnormally low cognitive function.
conclusionOur results suggest that weather conditions should be strongly considered when assessing the physical performance of older adults in the context of clinical practice and clinical research as examination in hot weather might lead to false conclusions on the participants' abilities.
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