Evidence map›Paper›PMID 41289187›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2025

Balancing flow arrest and aspiration: The relationship between balloon guide catheters, large-bore aspiration, and first pass effect in mechanical thrombectomy.

Danielle C Brown, Manisha Koneru, Jane Khalife, Hamza A Shaikh, Joshua Santucci, Ahmad A Ballout, Pratit D Patel, Karol Budohoski, Craig Kilburg, Robert C Rennert and 13 more

Expression of concernAbstract read
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In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It carries an expression of concern. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors.

Danielle C BrownCooper Medical School of Rowan University, Camden, NJ, USA.ORCID 0009-0003-3292-9033
Manisha KoneruCooper Medical School of Rowan University, Camden, NJ, USA.
Jane KhalifeCooper Neurological Institute, Cooper University Health Care, Camden, NJ, USA.
Hamza A ShaikhCooper Neurological Institute, Cooper University Health Care, Camden, NJ, USA.ORCID 0000-0001-8163-4600
Joshua SantucciCooper Neurological Institute, Cooper University Health Care, Camden, NJ, USA.
Ahmad A BalloutCooper Neurological Institute, Cooper University Health Care, Camden, NJ, USA.
Pratit D PatelCooper Neurological Institute, Cooper University Health Care, Camden, NJ, USA.
Karol BudohoskiDepartment of Neurosurgery, University of Utah Health, Salt Lake City, UT, USA.
Craig KilburgDepartment of Neurosurgery, University of Utah Health, Salt Lake City, UT, USA.
Robert C RennertDepartment of Neurosurgery, University of Utah Health, Salt Lake City, UT, USA.
Omid ShorakaDepartment of Neurosurgery, University of Utah Health, Salt Lake City, UT, USA.ORCID 0000-0003-1387-3866
Diwas GautamUniversity of Utah Spencer Fox Eccles School of Medicine, Salt Lake City, UT, USA.
Jackson AubreyUniversity of Utah Spencer Fox Eccles School of Medicine, Salt Lake City, UT, USA.
Julian BrownUniversity of Utah Spencer Fox Eccles School of Medicine, Salt Lake City, UT, USA.
Leonardo Cruz-CriolloDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Nashwa AbdelhakimDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Anderson BritoDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.ORCID 0000-0001-8646-5578
Ajith J ThomasCooper Neurological Institute, Cooper University Health Care, Camden, NJ, USA.
Tudor G JovinCooper Neurological Institute, Cooper University Health Care, Camden, NJ, USA.
Edgar A SamaniegoDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Santiago Ortega-GutierrezDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.ORCID 0000-0002-3408-1297
Ramesh GrandhiDepartment of Neurosurgery, University of Utah Health, Salt Lake City, UT, USA.ORCID 0000-0001-9000-6083
Daniel A TonettiCooper Neurological Institute, Cooper University Health Care, Camden, NJ, USA.ORCID 0000-0002-9258-1820

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundBalloon guide catheters (BGCs) have been associated with higher rates of first pass effect (FPE) in endovascular thrombectomy. Large-bore aspiration catheters (ACs) placed at the face of the embolus may mimic the flow arrest effect seen with BGCs; combined use and its effect on FPE have not been previously well-studied. This study aims to evaluate the impact of this dual-device strategy on achieving FPE.MethodsWe conducted a retrospective cohort study across three sites (2018-2024). A multicenter registry was queried for adult patients with anterior circulation acute ischemic stroke treated with thrombectomy. The primary outcome was rate of FPE (modified Treatment in Cerebral Infarction (mTICI) 2C/3 on the first pass). Multivariable logistic regressions for likelihood of FPE were performed.Results973 patients were included, with a median age of 69 years (IQR 59-79). BGCs were used in 26.3%. Large-bore ACs were used in 68.7%. In most cases, large-bore ACs were used without a BGC (BGC-: 77.5% vs. BGC+: 43.8%,

Indexed as

aspiration catheterballoon guide catheterFirst pass effectischemic strokethrombectomy

Identifiers

PMID41289187
PMCPMC12646947

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.