Evidence map›Paper›PMID 41288943›Full record

ArticleJournal of patient-reported outcomes2025

Predictors of impaired quality of life among colorectal cancer survivors: a cross-sectional study.

Abdulrahman Alotaibi, Seon Hahn Kim, Atyaf Alzahrani, Essa Alazmi, Mohammed Musslem, Nada Alharbi, Alaaeldin Darewish, Maha Eltaher, Sakher Abdullah, Shamel Soaida and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of patient-reported outcomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Abdulrahman AlotaibiDepartment of Surgery, Faculty of Medicine, University of Jeddah, Hamza bin Qasim Street, Al Sharafeyah, P. O. Box: 34, Jeddah, 21959, Saudi Arabia. aalotaibi@uj.edu.sa.ORCID http://orcid.org/0000-0001-8444-7229
Seon Hahn KimDepartment of Surgery, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Atyaf AlzahraniDepartment of Surgery, Faculty of Medicine, University of Jeddah, Hamza bin Qasim Street, Al Sharafeyah, P. O. Box: 34, Jeddah, 21959, Saudi Arabia.
Essa AlazmiDepartment of Surgery, Faculty of Medicine, University of Jeddah, Hamza bin Qasim Street, Al Sharafeyah, P. O. Box: 34, Jeddah, 21959, Saudi Arabia.
Mohammed MusslemDepartment of Surgery, Faculty of Medicine, University of Jeddah, Hamza bin Qasim Street, Al Sharafeyah, P. O. Box: 34, Jeddah, 21959, Saudi Arabia.
Nada AlharbiDepartment of Surgery, Faculty of Medicine, University of Jeddah, Hamza bin Qasim Street, Al Sharafeyah, P. O. Box: 34, Jeddah, 21959, Saudi Arabia.
Alaaeldin DarewishDepartment of Hematology and Oncology, Dr. Soliman Fakeeh Hospital, Jeddah, Saudi Arabia.
Maha EltaherDepartment of Radiation Oncology, National Cancer Institute, Cairo University, Cairo, Egypt.
Sakher AbdullahDepartment of Hematology and Oncology, Dr. Soliman Fakeeh Hospital, Jeddah, Saudi Arabia.
Shamel SoaidaDepartment of Clinical Oncology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Tarek MohammedDepartment of Hematology and Oncology, Dr. Soliman Fakeeh Hospital, Jeddah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundComprehensive research on the specific factors affecting the quality of life (QOL) of patients with colorectal cancer (CRC) is lacking. We investigated patient factors affecting QOL in this population. METHODOLOGY: We conducted a cross-sectional study at Dr. Suliman Fakeeh Hospital, a private tertiary center in Jeddah City, KSA. We used the validated Arabic versions of the Cancer Quality of Life Questionnaire-30 (QLQ-30) and Colorectal Cancer Quality of Life Questionnaire-29 (QLQ-CR29) in patients with CRC. We used a generalized linear model to analyze the data. Significant linear correlations between functional and symptom scores and 11 factors, including age, sex, tumor site and stage, comorbidities, surgery type/approach, leaks, stoma, and neoadjuvant or adjuvant therapy, were detected.

resultsA total of 104 participants answered the survey. The mean global health score was 72.43 (95% confidence interval [CI] 68.18-76.52). Cognitive and physical function scored highest and lowest on the QLQ-30, with a mean of 76.92 (95% CI 71.47-81.73) and 24.92 (95% CI 65.57-74.61), respectively. The worst symptom was insomnia, with a mean of 42.30 (95% CI 36.21-48.71). The most distressing symptoms on the QLQ-CR29 were stoma embarrassment and bloating, with a mean of 41.34 (95% CI 24.67-58.01). Tumor stage and stoma were the two most significant factors for predicting poor QOL. The factors influencing impotence and male libido included age, tumor stage, comorbidities, and the use of chemoradiotherapy.

conclusionsA one-unit increase in tumor stage was correlated with a 4.88-unit decrease in the global health status score, whereas a stoma was linked to a 22-fold reduction in social function scores. Advanced tumor stage and the presence of a stoma significantly affected patients' functional status and symptoms.

Indexed as

Cancer SurvivorsColorectal NeoplasmsQuality of LifeAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedSaudi ArabiaSurveys and QuestionnairesColon cancerQuality of lifeRectal cancerSurgery

Identifiers

PMID41288943
PMCPMC12647477

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.