ArticleEuropean geriatric medicine2026
Trends in hospital admissions and clinical complexity in centenarians: a nationwide population-based study in Spain (2004-2020).
Article in European geriatric medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Article
- Clinical characteristics, frailty, and one-year survival outcomes in centenarian patients presenting to the emergency department.BMC geriatrics · 2026Observational
- Critical illness at extreme age: outcomes and clinical characteristics of centenarian ICU admissions in Australia and New Zealand.Critical care (London, England) · 2026Article
- The Impact of Public Health Interventions on the Frequency and Duration of Hospitalisations Among Seniors in Poland-An Analysis Covering the Years 2017-2018.Journal of clinical medicine · 2025Article
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8 authors.
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Abstract
purposeThe aim of this study is to describe nationwide trends in clinical complexity, principal diagnoses, and in-hospital outcomes among centenarian hospital admissions in Spain, from 2004 to 2020.
methodsThis study is a retrospective, population-based study using the Spanish National Hospital Discharge Database. All unplanned admissions of patients aged ≥ 100 years were analyzed across three periods (2004-2010, 2011-2015, 2016-2020). Trends in comorbidity, diagnoses, complications, mortality, and length of stay (LOS) were assessed using joinpoint regression models.
resultsA total of 43,730 hospital admissions were analyzed. The prevalence of severe comorbidity rose from 17.6 to 31.8% (p < 0.001), and multimorbidity from 61.4 to 76.6% (p < 0.001), with parallel rises in dementia and other frailty-related conditions. Infections became the leading cause of admission (p < 0.001), particularly respiratory (from 18.4 to 26.1%), and urinary infections (from 4.2 to 7.9%). All types of in-hospital complications rose steadily, with an upward trend in patients with ≥ 3 complications, especially in the last 5 years (Annual percent changes (APC) = 14.9%; 95% confidence interval (CI) 9.7%; 20.4%) and among women (APC = 15.9%; 95% CI 10.7%; 21.5%). In-hospital mortality rose modestly (APC = 1.0%; 95% CI 0.5%; 1.6%), while average LOS decreased from 8.7 ± 10.5 to 7.3 ± 7.3 days (p < 0.001). Discharges to nursing homes increased from 2.1 to 4.8% (p < 0.001).
conclusionCentenarians admitted to Spanish hospitals over the last two decades showed increasing clinical complexity and complications, with infections as the leading cause of admission and a modest rise in mortality despite a shorter LOS. These findings highlight the need to adapt healthcare models for this growing and vulnerable population.
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