Evidence map›Paper›PMID 41288891›Full record

ArticleJournal of ophthalmic inflammation and infection2025

Bilateral endogenous fungal endophthalmitis following elective surgical abortion: a single center case series.

Viet Q Chau, Jesse D Sengillo, Flavius A Beca, Julia L Hudson, Thomas A Albini, Harry W Flynn

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Article in Journal of ophthalmic inflammation and infection, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Viet Q ChauAssociated Retinal Consultants/Beaumont Health, Royal Oak, MI, USA.
Jesse D SengilloDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA.
Flavius A BecaMid-Atlantic Retina, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA.
Julia L HudsonAssociated Vitreoretinal and Uveitis Consultants, Indianapolis, IN, USA.
Thomas A AlbiniDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA.
Harry W FlynnDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA. hflynn@med.miami.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo describe the clinical features and management of three cases of bilateral endogenous fungal endophthalmitis following elective surgical abortion performed at the same outpatient surgical center.

methodsCase series. OBSERVATIONS: Three immunocompetent women presented with vision loss days to weeks following elective surgical abortions performed at a single outpatient clinic. Initial visual acuities ranged from 20/20 to 20/300. Fundoscopic examination revealed multiple white round chorioretinal lesions with vitreous infiltration bilaterally in all three patients. Vitreous tap samples were obtained for culture and broad-spectrum intravitreal antimicrobials were administered. Despite negative cultures and systemic workup, the clinical presentation was consistent with fungal endophthalmitis. All patients received systemic and intravitreal antifungal therapy, leading to gradual resolution of lesions and improvement of visual acuity to 20/25 or better in all eyes.

conclusionsThis cases series represents the first reported cluster of endogenous fungal endophthalmitis following surgical abortion. Prompt recognition and treatment with intravitreal and systemic antifungals can result in favorable outcomes. The findings highlight the importance of stringent sterilization protocols in outpatient surgical settings and the need for heighted clinical suspicion in similar presentations.

Indexed as

Antifungal therapyEndogenous fungal endophthalmitisSurgical abortion

Identifiers

PMID41288891
PMCPMC12647472

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