ArticleBioresources and bioprocessing2025
Formulation and evaluation of ulvan-functionalized cumin oil nanoemulsions for antioxidant, anti-photoaging, and anti-melanogenesis activities in skin cells.
Article in Bioresources and bioprocessing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Development and evaluation of Sargassum polysaccharides-algal oil nanoemulsion for intranasal treatment of allergic rhinitis.Bioresources and bioprocessing · 2026Article
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6 authors.
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Abstract
Growing interest in natural skincare solutions has spotlighted bioactive substances like ulvan and cumin essential oil, valued for their roles in combating oxidative stress and inflammation. In this study, cumin oil-based nanoemulsions with and without ulvan extract (CC@NE and UP-CC@NE) were developed using ultrasonication and evaluated for their potential in protecting against oxidative stress, photoaging, and melanogenesis. The formulations exhibited droplet sizes below 100 nm, low polydispersity indices (PDI < 0.2), and negative zeta potentials (- 4.67 to - 11.90 mV), indicating good stability. In vitro assays demonstrated concentration-dependent antioxidant activity, as well as inhibition of tyrosinase, collagenase, and elastase. Both nanoemulsions maintained over 70% cell viability in L929 fibroblasts at 0.25% concentration. In HaCaT keratinocytes, 0.25% nanoemulsions significantly suppressed the production of reactive oxygen species (ROS) triggered by hydrogen peroxide (H
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