Evidence map›Paper›PMID 41288722›Full record

SynthesisClinical neuroradiology2026

General Versus Non-General Anesthesia in Endovascular Thrombectomy for Distal/Medium Vessel Occlusions: A Systematic Review and Meta-Analysis.

Luiz Guilherme Silva Almeida, Ocílio Ribeiro Gonçalves, Mariana Lee Han, Yasmin Picanço Silva, Lucca Tamara Alves Carretta, Marcelo Costa, Paweł Łajczak, Luiz Felipe Simões Antunes Nery Dos Santos, Rafael Torres Fonseca Dos Santos, Ahmet Günkan and 1 more

Abstract readSystematic ReviewMeta-AnalysisComparative Study
PubMed Publisher
In one paragraph

Synthesis in Clinical neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Luiz Guilherme Silva AlmeidaDepartment of Medicine, Catholic University of Brasília, QS 07 Lote 01 Bloco L, Taguatinga Sul/DF, 71966-700, Brasília, Brazil. lguilherme1109@gmail.com.ORCID http://orcid.org/0009-0008-4476-1174
Ocílio Ribeiro GonçalvesDepartment of Medicine, Federal University of Piauí, Teresina, Brazil.ORCID http://orcid.org/0009-0008-6103-8420
Mariana Lee HanDepartment of Medicine, University of São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-8291-6474
Yasmin Picanço SilvaHealthcare Institution of South Iceland, Selfoss, Iceland.ORCID http://orcid.org/0009-0003-5728-4964
Lucca Tamara Alves CarrettaDepartment of Medicine, Santa Casa de Misericórdia de Vitória, Vitória, Brazil.ORCID http://orcid.org/0009-0005-1942-2363
Marcelo CostaDepartment of Medicine, Wright State University Boonshoft School of Medicine, Fairborn, OH, USA.ORCID http://orcid.org/0009-0001-8672-1831
Paweł ŁajczakMedical University of Silesia, Katowice, Poland.ORCID http://orcid.org/0000-0003-0281-5417
Luiz Felipe Simões Antunes Nery Dos SantosUniversity Institute of Health Sciences, Fundación H. A. Barceló, La Rioja, Argentina.ORCID http://orcid.org/0009-0006-0151-403X
Rafael Torres Fonseca Dos SantosMedical Education Institute Vista Carioca, Rio de Janeiro, Brazil.ORCID http://orcid.org/0009-0001-3698-8845
Ahmet GünkanDepartment of Radiology, University of Arizona, Tucson, USA.ORCID http://orcid.org/0000-0002-6236-5633
Pascal JabbourDepartment of Neurological Surgery, Thomas Jefferson University, Philadelphia, USA.ORCID http://orcid.org/0000-0002-8965-2413

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWith the expanding use of endovascular thrombectomy (EVT) for distal and medium vessel occlusions (DMVOs), evaluating how anesthesia type affects clinical outcomes is essential. This meta-analysis compared outcomes between general anesthesia (GA) and non-GA in patients undergoing EVT for DMVOs.

methodsWe systematically searched PubMed, Embase, Cochrane Library, and Web of Science for eligible studies. Primary outcomes included successful reperfusion, 90-day mortality, excellent functional outcome (Modified Rankin Scale [mRS] 0-1), and symptomatic intracranial hemorrhage (sICH). Risk ratios (RR) with 95% confidence intervals (CI) were calculated using the Mantel-Haenszel method and a random-effects model. Heterogeneity was assessed with I

resultsFive studies comprising 1643 patients were included. There was no significant difference in successful reperfusion between GA and non-GA groups (RR 1.01; 95% CI 0.94-1.08; I

conclusionGA was linked to increased 90-day mortality in EVT for DMVOs, with no differences in reperfusion or functional recovery. A possible higher risk of sICH was noted. Further prospective studies are needed to guide anesthetic strategy.

Indexed as

Anesthesia, GeneralEndovascular ProceduresThrombectomyHumansTreatment OutcomeConscious sedationDistal vessel occlusionEndovascular thrombectomyGeneral anesthesiaMedium vessel occlusion

Identifiers

PMID41288722

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.