Evidence map›Paper›PMID 41288703›Full record

ReviewEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

Vestibular granuloma as a rare post-stapedotomy complication: case report and literature review.

Riccardo De Lellis, Filippo Valentini, Mara Riminucci, Alessandro Corsi, Francesca Yoshie Russo, Daniele De Seta

Abstract readCase ReportsReview
In one paragraph

Review in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Riccardo De LellisDepartment of Sense Organs, Sapienza University of Rome, Viale del Policlinico 155, Rome, 00161, Italy.
Filippo ValentiniDepartment of Sense Organs, Sapienza University of Rome, Viale del Policlinico 155, Rome, 00161, Italy. filippo.valentini@uniroma1.it.ORCID http://orcid.org/0009-0007-4386-8976
Mara RiminucciDepartment of Molecular Medicine, Section of Pathology, Sapienza University of Rome, Viale del Policlinico 155, Rome, 00161, Italy.
Alessandro CorsiDepartment of Molecular Medicine, Section of Pathology, Sapienza University of Rome, Viale del Policlinico 155, Rome, 00161, Italy.
Francesca Yoshie RussoDepartment of Sense Organs, Sapienza University of Rome, Viale del Policlinico 155, Rome, 00161, Italy.
Daniele De SetaDepartment of Sense Organs, Sapienza University of Rome, Viale del Policlinico 155, Rome, 00161, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVestibular granuloma is a rare complication of a common surgical procedure, such as stapedotomy; it can significantly impact the outcome of surgery, leading to severe impairment and deterioration in the patient's quality of life. CASE REPORT: A 59-year-old male underwent stapedotomy with a titanium prosthesis. Initially, hearing function improved but, within days, the patient developed vertigo and worsened hearing loss. HR CT of temporal bone revealed soft tissue in the tympanic cavity, prompting revision surgery. Granulomatous tissue surrounding the prosthesis was removed, leading to symptom relief. However, the patient later developed Persistent Postural-Perceptual Dizziness (PPPD), requiring SSRI therapy. DISCUSSION: The sudden onset of persistent vertigo and hearing loss, that rapidly worsens in post-operative setting, represents a crucial red flag for the surgical team. Hearing assessments and imaging play a key role in quickly diagnosing the cause of these complications, which may be attributed to an inflammatory response at the surgical site, possibly due to granuloma formation. This enables the surgical équipe to swiftly implement appropriate care strategies for the patient, even in the presence of additional and subsequent complications like PPPD, which requires a comprehensive, multimodal approach to treatment.

conclusionThis case highlights the risk of a series of complications after surgery and even after reoperation, ultimately requiring conservative multimodal treatment and follow-up. Early recognition and coordinated care are essential for optimal long-term management of patients, even in the presence of unfavorable outcomes and complications.

Indexed as

GranulomaPostoperative ComplicationsStapes SurgeryVestibular DiseasesHumansMaleMiddle AgedReoperationTomography, X-Ray ComputedVertigoComplicationGranulomaOtosclerosisPPPDStapedotomyStapes-prosthesisVestibular disorders

Identifiers

PMID41288703
PMCPMC13002652

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.