Evidence map›Paper›PMID 41288355›Full record

ArticleApplied and environmental microbiology2025

Benchmarking the PAM compatibility of Cas12a variants for high-throughput yeast genetic variant engineering.

Weiyu Xie, Zhenkun Cai, Zehua Bao

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Weiyu XieKey Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, Zhejiang, China.
Zhenkun CaiKey Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, Zhejiang, China.
Zehua BaoKey Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, Zhejiang, China.ORCID 0000-0002-5519-4864

Funding

Fundamental Research Funds for the Central Universities 226-2025-00043, 226-2022-00214National Key Research and Development Program of China 2023YFF1204500National Natural Science Foundation of China 22308316
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacterial ProteinsCRISPR-Associated ProteinsCRISPR-Cas SystemsEndodeoxyribonucleasesGene EditingGenetic EngineeringSaccharomyces cerevisiaeBenchmarkingGenetic VariationBacterial ProteinsCas12a proteinCRISPR-Associated ProteinsEndodeoxyribonucleasesCas12aCRISPRgene editingSaccharomyces cerevisiae

Identifiers

PMID41288355
PMCPMC12724276

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.