Microbial Surface Glycan Probe Isolates Anti-l-Rhamnose Antibodies from Human Serum for Bacterial Detection.

Hersa Milawati, Mia Sheshova, Joanna Joo, Tania J Lupoli

Abstract read

In one paragraph

Article in ACS infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Hersa MilawatiDepartment of Chemistry, New York University, New York, New York 10003, United States.

Mia SheshovaDepartment of Chemistry, New York University, New York, New York 10003, United States.

Joanna JooDepartment of Chemistry, New York University, New York, New York 10003, United States.ORCID 0009-0006-0892-375X

Tania J LupoliDepartment of Chemistry, New York University, New York, New York 10003, United States.ORCID 0000-0002-0989-2565

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MARK Reid PHILIPS · 1985 to 2026

$83.1M

Probing Glycan Polymer Patterns on Bacterial Cell SurfacesR35GM142887 · NIGMS · NEW YORK UNIVERSITY · PI LUPOLI, TANIA · 2021 to 2025

$2.1M

NCI NIH HHS P30 CA016087NIGMS NIH HHS R35 GM142887

6 · The paper itself

Abstract

Bacterial strains are distinguished by surface glycans composed of defined sugar sequences that include "rare" monosaccharides, which are absent in human glycans and help to mediate host-microbe interactions. One of the most prevalent rare sugars is l-Rhamnose (l-Rha), and human sera are generally enriched in anti-l-Rha antibodies; however, the source of l-Rha antigens is unknown. Here, we synthesize a surface glycan l-Rha-

Indexed as

Antibodies, BacterialBacteriaPolysaccharidesRhamnoseDisaccharidesEpitopesHumansImmunoglobulin GAntibodies, BacterialDisaccharidesEpitopesImmunoglobulin GPolysaccharidesRhamnoseanti-glycan antibodiesbacteriahuman serumRare sugarsrhamnose

Identifiers

PMID41288253

DOI10.1021/acsinfecdis.5c00757

PMCPMC12706776

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.