Evidence map›Paper›PMID 41288105›Full record

ArticlemSphere2025

Specific and versatile monoclonal antibodies for hantavirus research.

Autumn LaPointe, Kimberly Martinez, Christina Shou, Inessa Manuelyan, Jason Botten, Alison M Kell

Abstract read
In one paragraph

Article in mSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Autumn LaPointeDepartment of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.ORCID 0000-0002-2560-8624
Kimberly MartinezDepartment of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
Christina ShouDepartment of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
Inessa ManuelyanDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, Vermont, USA.
Jason BottenDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, Vermont, USA.
Alison M KellDepartment of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.ORCID 0000-0001-5550-1038

Funding

Unfolded Protein Response and Autophagy in T Helper Cell Effector FunctionP20GM121176 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Samuel Joseph Endicott · 2017 to 2026
$24.9M
Biology of Infectious Diseases &InflammationT32AI007538 · NIAID · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Michelle A Ozbun · 1998 to 2026
$5.2M
Mapping the virus-host interactions that determine interferon resistance of Seoul orthohantavirusR21AI175721 · NIAID · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI KELL, ALISON · 2024 to 2025
$428k
National Institute of Allergy and Infectious Diseases 1R21AI175721-01A1NIAID NIH HHS R21 AI175721NIAID NIH HHS T32 AI007538NIGMS NIH HHS P20 GM121176NIGMS NIH HHS T32AI007538
6 · The paper itself

Abstract

Rodent-borne hantaviruses pose a continual public health threat to humans through zoonotic transmission, with case fatality rates of up to 50% in some cases. Human infections can lead to hemorrhagic fever with renal syndrome (HFRS) or hantavirus cardiopulmonary syndrome depending on the viral species. Despite the morbidity and mortality associated with this family of viruses, no anti-viral therapeutics or vaccines are available to treat and prevent hantavirus disease. The relative shortage of commercially available reagents to study hantavirus infections

Indexed as

Antibodies, MonoclonalAntibodies, ViralOrthohantavirusAnimalsHantavirus InfectionsHumansMiceMice, Inbred BALB CSeoul virusViral ProteinsAntibodies, MonoclonalAntibodies, ViralViral Proteinshantavirusimmunofluorescencemonoclonal antibodiesWestern blotting

Identifiers

PMID41288105
PMCPMC12724165

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.