Evidence map›Paper›PMID 41287793›Full record

ArticleFrontiers in genetics2025

Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (

Ting Yang, Xiaolu Lin, Rui Chen, Ruiqi Wang, Tong Li, Fulong Shen, Xiaowei Zhang, Lianghua Lai, Bing Lu, Jiliang Wei and 1 more

Abstract read
In one paragraph

Article in Frontiers in genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Journal of microbiology and biotechnology · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ting YangCollege of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.
Xiaolu Lin *Institute of Tobacco Science, Longyan Tobacco Company, Longyan, China.
Rui ChenCollege of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.
Ruiqi WangCollege of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.
Tong LiCollege of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.
Fulong ShenInstitute of Tobacco Science, Longyan Tobacco Company, Longyan, China.
Xiaowei ZhangInstitute of Tobacco Science, Longyan Tobacco Company, Longyan, China.
Lianghua LaiInstitute of Tobacco Science, Longyan Tobacco Company, Longyan, China.
Bing LuInstitute of Tobacco Science, Longyan Tobacco Company, Longyan, China.
Jiliang WeiInstitute of Tobacco Science, Longyan Tobacco Company, Longyan, China.
Xiaofang XieCollege of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optimizing fermentation duration is critical for producing high-quality cigar tobacco leaves This study examines changes in microorganisms and metabolites during CTL fermentation at four time points: 0 days (T0), 25 days (T1), 50 days (T2), and 75 days (T3). We observed a decreasing trend in total soluble sugars, starch, total nitrogen, and nicotine levels as fermentation progressed. Notably, chemical components stabilized after T2 stages. The microbial community showed dynamic fluctuations, with alpha diversity indices (Shannon, ACE, Pielou's evenness, and Chao-2) reaching equilibrium at T2 and maintaining stability thereafter. Dominant genera such as

Indexed as

cigar tobacco leaves (CTLs)fermentationmetabolitesmicrobial communitymulti-omics

Identifiers

PMID41287793
PMCPMC12640762

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.