Evidence map›Paper›PMID 41287768›Full record

ArticleJournal of inflammation research2025

SIRT1 Enhancement is Required for the Induction of Anti-Inflammatory Effect of Micheliolide in Carbon Tetrachloride Induced Liver Fibrosis in Mice.

Chengye Jin, Aoqing Jiang, Jieming Chang, Yirong Hu, Yichen Wang, Rui Zhao, Jingwei Shi, Hongyan Wu, Zhongliang Han, Zhaoguo Liu

Abstract read
In one paragraph

Article in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chengye Jin *School of Pharmacy, Nantong University, Nantong, Jiangsu, People's Republic of China.
Aoqing Jiang *School of Pharmacy, Nantong University, Nantong, Jiangsu, People's Republic of China.
Jieming ChangSchool of Pharmacy, Nantong University, Nantong, Jiangsu, People's Republic of China.
Yirong HuSchool of Pharmacy, Nantong University, Nantong, Jiangsu, People's Republic of China.
Yichen WangSchool of Pharmacy, Nantong University, Nantong, Jiangsu, People's Republic of China.
Rui ZhaoSchool of Pharmacy, Nantong University, Nantong, Jiangsu, People's Republic of China.
Jingwei ShiSchool of Medicine, Nantong University, Nantong, Jiangsu, People's Republic of China.
Hongyan WuInstitute of Biomedical Technology, Jiangsu Medical College, Yancheng, Jiangsu, People's Republic of China.
Zhongliang HanSchool of Pharmacy, Nantong University, Nantong, Jiangsu, People's Republic of China.
Zhaoguo LiuSchool of Pharmacy, Nantong University, Nantong, Jiangsu, People's Republic of China.ORCID 0000-0001-6311-8338

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Micheliolide (MCL), a guaianolide sesquiterpene lactone isolated from Methods: Liver fibrosis model was established in mice via intraperitoneal (i.p.) injections of 10% CCl Results: MCL attenuated CCl Conclusion: MCL mitigates CCl

Indexed as

carbon tetrachlorideinflammationliver fibrosismicheliolideSIRT1

Identifiers

PMID41287768
PMCPMC12640647

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.