Evidence map›Paper›PMID 41287724›Full record

ArticleCureus2025

Congenital Leukemia: Presentation of Three Cases.

Zuzanna Karczmarzyk, Magdalena Szuba, Joanna Krupa, Natalia Czaplińska, Bożena Kociszewska-Najman

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zuzanna KarczmarzykProNeo Student Scientific Group, Department of Neonatology and Rare Diseases, Medical University of Warsaw, Warsaw, POL.
Magdalena SzubaProNeo Student Scientific Group, Department of Neonatology and Rare Diseases, Medical University of Warsaw, Warsaw, POL.
Joanna KrupaProNeo Student Scientific Group, Department of Neonatology and Rare Diseases, Medical University of Warsaw, Warsaw, POL.
Natalia CzaplińskaDepartment of Neonatology and Rare Diseases, Medical University of Warsaw, Warsaw, POL.
Bożena Kociszewska-NajmanDepartment of Neonatology and Rare Diseases, Medical University of Warsaw, Warsaw, POL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital leukemia is a very rare but severe disease diagnosed within the first 28 days of life. Common symptoms include hepatosplenomegaly, leukemia cutis, pallor, petechiae, leukocytosis, and thrombocytopenia. This report presents three full-term newborns diagnosed with congenital leukemia. Examination of all three patients showed hepatosplenomegaly, petechiae, and thrombocytopenia, although the symptoms appeared at a different time in each case. Due to the non-specific nature of early symptoms, cytological analysis, cytogenetic testing, and immunophenotyping are essential for establishing a definitive diagnosis. Congenital leukemia is a rare condition that requires early diagnosis, personalized treatment, and ongoing research. Despite progress in neonatal care, the prognosis of this condition remains poor, highlighting the importance of developing better diagnostic tools and therapeutic strategies.

Indexed as

acute myeloid leukemiacongenital leukemiahepatosplenomegaly in infancyhyperleukocytosis (hl)infantneonatal leukemia

Identifiers

PMID41287724
PMCPMC12640626

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.