Evidence map›Paper›PMID 41287719›Full record

ArticleCureus2025

Lurking in Ambush: A Case Report of Probable Creutzfeldt-Jakob Disease From Rural Kerala, India.

Issac Georgy, Thomas V Pulickal, Calvin Jose, Alan J Kannemkuzhiyil, Avaroth Krishnadas

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Issac GeorgyInternal Medicine, Jayamatha Hospital, Kollam, IND.
Thomas V PulickalEmergency Medicine, All India Institute of Medical Sciences, Bhubaneswar, Bhubaneswar, IND.
Calvin JoseInternal Medicine, Good Shepherd Hospital, Wayanad, IND.
Alan J KannemkuzhiyilFamily and Community Medicine, Good Shepherd Hospital, Wayanad, IND.
Avaroth KrishnadasInternal Medicine, Good Shepherd Hospital, Wayanad, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Creutzfeldt-Jakob disease (CJD) is a rare, rapidly progressive neurodegenerative disorder caused by prion proteins. This case report describes a probable instance of sporadic CJD in an elderly male from rural Kerala, India. The patient presented with rapidly evolving neurocognitive decline, myoclonus, and characteristic MRI and EEG findings. Despite limited resources, a probable diagnosis was established through clinical evaluation and supportive investigations. This case highlights the challenges of diagnosing rare neurological disorders in resource-constrained settings and underscores the importance of clinical vigilance in rural healthcare practice.

Indexed as

creutzfeldt-jakob diseaseprionsrapidly progressive dementiarural keralasporadic creutzfeldt-jakob disease

Identifiers

PMID41287719
PMCPMC12640693

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.