Evidence map›Paper›PMID 41287670›Full record

ArticleCureus2025

Widening Racial and Sociodemographic Disparities in Cardiovascular Disease Death Counts in the United States: A Comprehensive Analysis of 2018-2023 National Data.

Prashant S Gupta, Vatsalkumar Jetani, Hardik D Desai, Sumit Kyada, Shivani B Sonani, Gokul Gopi, Sankalp Acharya, Yash Trivedi, Sandeep Kotnani, Hardik Jain

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Prashant S GuptaDepartment of Medicine, Surat Municipal Institute of Medical Education and Research, Surat, IND.
Vatsalkumar JetaniDepartment of Medicine, Epsom and St Helier University Hospitals, London, GBR.
Hardik D DesaiDepartment of Research, Independent Public Health Research, Ahmedabad, IND.
Sumit KyadaDepartment of Family Medicine, Ellis Hospital, Schenectady, USA.
Shivani B SonaniDepartment of Family Medicine, Ellis Hospital, Schenectady, USA.
Gokul GopiDepartment of Internal Medicine, Ascension Sacred Hearts, Pensacola, USA.
Sankalp AcharyaDepartment of Internal Medicine, Monmouth Medical Center, Long Branch, USA.
Yash TrivediDepartment of Internal Medicine, Nassau University Medical Center, East Meadow, USA.
Sandeep KotnaniDepartment of Internal Medicine, Monmouth Medical Center, Long Branch, USA.
Hardik JainDepartment of Internal Medicine, Allegheny General Hospital, Pittsburgh, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Cardiovascular disease (CVD) remains the leading cause of death in the United States, yet recent trends suggest widening disparities across race, sex, geography, and socioeconomic groups. Methods We conducted a retrospective, population-based trend analysis of mortality data from the National Vital Statistics System (NVSS), 2018-2023, accessed via the Centers for Disease Control and Prevention (CDC) Wide-ranging ONline Data for Epidemiologic Research (WONDER) online Database. Deaths with CVD (International Classification of Diseases, 10th revision (ICD-10): I00-I99) as the underlying cause were included. Mortality counts were stratified by race (15 single-race categories), sex, age, census region, 2013 urbanization level, Hispanic origin, and education. Cause-specific analyses covered major ICD-coded CVD subcategories. Annualized percentage change (APC) and 95% confidence intervals (CI) were estimated using log-linear regression of annual counts. Results Between 2018 and 2023, there were 5.4 million CVD deaths nationwide, rising from 868,662 in 2018 to 915,973 in 2023. The steepest increases occurred in Pacific Islander (6.7%/year), Vietnamese (6.2%), and Asian Indian (6.1%) populations, while Whites individuals (1.2%) and Japanese (0.3%) showed minimal changes. By cause, ischemic and hypertensive heart diseases accounted for the largest gains. Regional increases were most pronounced in the South and West, and rural non-core areas exhibited the fastest growth. Younger adults (25-44 years) in Black individuals, Asian Indian, and American Indian groups showed APCs exceeding 5%. Women generally experienced higher APCs than men. Disparities were amplified by Hispanic origin and lower educational attainment. Conclusions CVD mortality in the United States is once again rising, with young adults, women, minority populations, rural residents, Hispanics, and the less educated experiencing the sharpest increases. These findings reveal a reversal of prior gains and underscore the urgent need for equity-focused prevention and policy strategies.

Indexed as

cardiovascular-related mortalitychronic disease epidemiologygender and racial inequitiesracial disparityunited states mortality

Identifiers

PMID41287670
PMCPMC12640433

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.