Evidence map›Paper›PMID 41287637›Full record

ArticleOpen research Europe2025

How the First Medical Imaging Cancer Atlas EUCAIM Was Populated: The Experience of a Reference Hospital.

Ana Penadés Blasco, Leonor Cerdá Alberich, Ana de Marco García, Carina Soler Pons, Irene Marín Radoszynski, Ricard Martínez, Damián Segrelles-Quilis, Ignacio Blanquer, Luis Martí-Bonmatí

Abstract read
In one paragraph

Article in Open research Europe, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ana Penadés BlascoBiomedical Imaging Research Group (GIBI230), La Fe Health Research Institute, Valencia, Spain, 46026, Spain.ORCID https://orcid.org/0000-0002-2979-2123
Leonor Cerdá AlberichBiomedical Imaging Research Group (GIBI230), La Fe Health Research Institute, Valencia, Spain, 46026, Spain.
Ana de Marco GarcíaBiomedical Imaging Research Group (GIBI230), La Fe Health Research Institute, Valencia, Spain, 46026, Spain.ORCID https://orcid.org/0009-0004-6906-3779
Carina Soler PonsBiomedical Imaging Research Group (GIBI230), La Fe Health Research Institute, Valencia, Spain, 46026, Spain.
Irene Marín RadoszynskiBiomedical Imaging Research Group (GIBI230), La Fe Health Research Institute, Valencia, Spain, 46026, Spain.ORCID https://orcid.org/0009-0001-1841-7379
Ricard MartínezIRTIC- Instituto Universitario de Investigación de Robótica y Tecnologías de la Información y Comunicación, Valencia, Spain, 46980, Spain.
Damián Segrelles-QuilisInstituto de Instrumentación para la Imagen Molecular, Universitat Politècnica de València, Valencia, Spain, 46011, Spain.
Ignacio BlanquerInstituto de Instrumentación para la Imagen Molecular, Universitat Politècnica de València, Valencia, Spain, 46011, Spain.
Luis Martí-BonmatíBiomedical Imaging Research Group (GIBI230), La Fe Health Research Institute, Valencia, Spain, 46026, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fragmentation and decentralization of medical data, including radiological imaging, continue to challenge large-scale observational research across Europe. Artificial Intelligence (AI) applied to big datasets is transforming diagnosis and treatments towards precision medicine across many diseases, yet the lack of findable, accessible, and interoperable datasets still limits model development, validation, and final clinical translation. The European Federation for Cancer Images (EUCAIM) project was launched in 2023 to address these challenges by establishing a secure centralized and federated infrastructure for the secondary use of large-scale oncological imaging and related clinical data. By consolidating fragmented datasets, EUCAIM lays the groundwork for harmonized data governance and trusted cross-border sharing. Implementing a robust documentation framework is essential to ensure regulatory compliance, safeguard data integrity, and support secure data flows across institutional and national boundaries, fully aligned with European regulations and ethical standards. EUCAIM builds on the AI for Health Imaging (AI4HI) initiative (Predictive In-silico Multiscale Analytics to support cancer personalized diagnosis and prognosis, empowered by imaging biomarkers - PRIMAGE, Accelerating the lab to market transition of AI tools for cancer management - CHAIMELEON, Novel pan-European imaging platform for artificial intelligence advances in oncology - EuCanImage, An AI Platform integrating imaging data and models, supporting precision care through prostate cancer's continuum - ProCancer-I, A multimodal AI-based toolbox and an interoperable health imaging repository for the empowerment of imaging analysis related to the diagnosis, prediction and follow-up of cancer - INCISIVE and integrates over 94 partners and more than 180 stakeholders spanning medical imaging, high performance computing, data standardization, innovation, and legal compliance. This large collaborative ecosystem reinforces EUCAIM's role as a reference for General Data Protection Regulation (GDPR) and European Health Data Space Regulation (EHDSR) adherence. This publication presents the real-world experience of integrating imaging and clinical data from a reference university hospital into the EUCAIM infrastructure. It outlines the procedural, ethical, and legal challenges encountered, and details the strategies implemented to ensure compliance with data protection regulations, including privacy, security, and ethical standards. These insights offer a practical framework for future large-scale oncological imaging datasets harmonization and AI development, contributing to scalable, reproducible, and legally compliant research that strengthens Europe's capacity for trustworthy AI-driven oncology solutions.

Indexed as

Artificial Intelligencecancer researchdata governancefederated infrastructuresinnovationmedical imagingsustainability

Identifiers

PMID41287637
PMCPMC12640480

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.