Evidence map›Paper›PMID 41287630›Full record

ArticleSAGE open medicine2025

Development and validation of a nomogram for predicting perforation in the early 24 h of acute appendicitis.

Yong Mei, Zhuo Huang, Zhi-Yuan Huang, Yan-Bing Shen, Zhang-Hao Liu, Qiao-Nuo Wei, Zhen Lan, Qin-Quan Zhang, Wen-Fei He, Wuerkaixi Abulaiti and 3 more

Abstract read
In one paragraph

Article in SAGE open medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Predictors of prolonged hospitalization and inflammation severity in acute appendicitis: a retrospective cohort study.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yong MeiSchool of Medicine, Wuhan University of Science and Technology, Hubei Province, China.ORCID https://orcid.org/0009-0001-4847-5246
Zhuo HuangSchool of Medicine, Wuhan University of Science and Technology, Hubei Province, China.
Zhi-Yuan HuangDepartment of General Surgery, People's Liberation Army General Hospital of Central Theater Command, Wuhan, Hubei Province, China.
Yan-Bing ShenDepartment of General Surgery, People's Liberation Army General Hospital of Central Theater Command, Wuhan, Hubei Province, China.
Zhang-Hao LiuSchool of Management, Lanzhou University, Gansu Province, China.
Qiao-Nuo WeiDepartment of Ophthalmology, Jiangmen Hospital Affiliated to Southern Medical University, Guangdong Province, China.
Zhen LanDepartment of General Surgery, People's Liberation Army General Hospital of Central Theater Command, Wuhan, Hubei Province, China.
Qin-Quan ZhangDepartment of General Surgery, People's Liberation Army General Hospital of Central Theater Command, Wuhan, Hubei Province, China.
Wen-Fei HeDepartment of General Surgery, People's Liberation Army General Hospital of Central Theater Command, Wuhan, Hubei Province, China.
Wuerkaixi AbulaitiDepartment of General Surgery, People's Liberation Army General Hospital of Central Theater Command, Wuhan, Hubei Province, China.
Nuo XuDepartment of General Surgery, People's Liberation Army General Hospital of Central Theater Command, Wuhan, Hubei Province, China.
Lian-Chun MaoDepartment of General Surgery, People's Liberation Army General Hospital of Central Theater Command, Wuhan, Hubei Province, China.
Wei-Dong JinDepartment of General Surgery, People's Liberation Army General Hospital of Central Theater Command, Wuhan, Hubei Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aimed to develop and validate a nomogram prediction model for identifying the risk of early perforation (within 24 h) in patients with acute appendicitis, using objective clinical and imaging indicators. Methods: A retrospective study was performed on 880 patients with acute appendicitis who underwent laparoscopic appendectomy within 24 h of symptom onset at the General Surgery Department of the Central Theater Command General Hospital between January 2011 and December 2022. Patients admitted from 2011 to 2020 were assigned to the modeling group ( Results: Appendiceal diameter, body temperature, white blood cell count, fibrinogen level, appendiceal fecalith, age, and diabetes mellitus were identified as independent predictors of early perforation in acute appendicitis within 24 h ( Conclusion: The nomogram prediction model incorporating appendiceal diameter, body temperature, white blood cell count, fibrinogen level, appendiceal fecalith, age, and diabetes mellitus demonstrates clinical utility in estimating the probability of perforation within 24 h in patients with acute appendicitis.

Indexed as

acute appendicitisearly perforationnomogrampredictive modelsrisk factors

Identifiers

PMID41287630
PMCPMC12640455

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.