ArticleYonsei medical journal2025
Trends in Health Expenditures for Chronic Disease Management: Hypertension, Diabetes Mellitus, and Dyslipidemia from 2013 to 2020.
Article in Yonsei medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Lactational Enrofloxacin Exposure Promotes Offspring Lipid Metabolic Disorder and Adiposity Involving Gut Microbiota-Derived LPS and PPARγ Signaling.Microorganisms · 2026Article
- Continuity of Care and Risks of Hospitalization and Mortality in COPD: A Nationwide Cohort Study.International journal of chronic obstructive pulmonary disease · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
purposeChronic diseases such as hypertension (HT), diabetes mellitus (DM), and dyslipidemia (LD) are leading contributors to healthcare expenditures globally, including in South Korea. This study aimed to analyze trends in health expenditures for managing these conditions, focusing on patient demographics, comorbidities, and complications, using real-world data from a tertiary care hospital. MATERIALS AND
methodsThis retrospective study utilized clinical data from Severance Hospital's Severance Clinical Research Analysis Portal (SCRAP) system, covering 2013 to 2020. Patients diagnosed with HT, DM, and LD were identified using ICD-10 codes. Generalized linear mixed models were applied to evaluate trends in health expenditures, and a Sankey diagram was used to visualize expenditure flows by patient subgroups and care categories.
resultsTotal health expenditures increased nearly threefold, from 157.2 billion KRW in 2013 to 444.8 billion KRW in 2020, driven primarily by rising reimbursable costs (67.1% to 84.1%). Per-patient expenditures decreased initially but stabilized by 2020. Patients with HT+DM incurred the highest per-patient costs, followed by those with HT alone. Complications, particularly cardiovascular and cerebrovascular diseases, significantly elevated costs, with inpatient care accounting for the largest expenditure share.
conclusionThe economic burden of managing chronic diseases is substantial, particularly for patients with multiple conditions or complications. Strengthening preventive care and integrated management strategies, alongside sustained financial support, is crucial for improving cost-efficiency in chronic disease care.
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Registered trials
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