ArticleJournal of Korean medical science2025
Performance of Allplex™ MG & AziR Assay for Detecting Macrolide-Resistant
Article in Journal of Korean medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Prevalence and Distribution of Antimicrobial Resistance-Associated Mutations inMicroorganisms · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
background
methodsUsing 279
resultsThe AziR assay targeting positions 2058 and 2059 in the 23S rRNA gene revealed that 133 and 146 cases, respectively, carried the wild and mutant types of adenosine, while sequencing detected the wild and mutant types in 134 and 145 cases, respectively. The AziR assay demonstrated a sensitivity of 100% (95% confidence interval [CI], 0.968-1) and specificity of 99.254% (95% CI, 0.953-1) in distinguishing wild type from mutant variants. Of the 279 samples, only six showed genetic discrepancies between the two tests: one wild type by sequencing was found to have A2059G by the AziR assay, two A2059Gs were discordant as A2058Ts, one A2059G was discordant as A2058G, and two A2058Gs by sequencing were reported as A2059Gs by the AziR assay.
conclusionOur results show that the AziR assay can identify specific mutants in a single reaction and demonstrates high sensitivity and specificity for detecting macrolide resistant
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