Evidence map›Paper›PMID 41287479›Full record

ArticleNano letters2025

Long-Term Stabilization and Storage of Peptide-Based Coacervate through Tyrosine-Rich Sequences and Polyphenol Network.

Mohammad Souri, Moumita Halder, Lubna Amer, Yong Hua, Benjamin Lam, Wonjun Yim, Zhicheng Jin, Jesse V Jokerst

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nano letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mohammad SouriAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, San Diego, La Jolla, San Diego, California 92093, United States.ORCID 0000-0001-9509-1336
Moumita HalderAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, San Diego, La Jolla, San Diego, California 92093, United States.ORCID 0009-0008-9113-8510
Lubna AmerMaterials Science and Engineering Program, University of California, San Diego, La Jolla, San Diego, California 92093, United States.ORCID 0000-0001-5715-5060
Yong HuaAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, San Diego, La Jolla, San Diego, California 92093, United States.
Benjamin LamAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, San Diego, La Jolla, San Diego, California 92093, United States.ORCID 0009-0004-3616-1583
Wonjun YimDepartment of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.ORCID 0000-0002-0242-7898
Zhicheng JinDepartment of Chemistry, Georgia State University, Atlanta, Georgia 30303, United States.ORCID 0000-0001-6072-7533
Jesse V JokerstAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, San Diego, La Jolla, San Diego, California 92093, United States.ORCID 0000-0003-2829-6408

Funding

U of Calif, San Diego Neuroscience Microscopy ImagingP30NS047101 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GLEESON, JOSEPH G, ZHENG, BINHAI · 2003 to 2022
$9.0M
JEOL JEM-1400Plus Transmission Electron MicroscopeS10OD023527 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FARQUHAR, MARILYN GIST · 2017 to 2017
$579k
New Tools to Image Tau Protein Form and FunctionR21AG091821 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2025 to 2025
$437k
MANTA ViewSizer 3011 Nanoparticle Characterization SystemS10OD023555 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2018 to 2018
$137k
NIA NIH HHS R21 AG091821NIH HHS S10 OD023527NIH HHS S10 OD023555NINDS NIH HHS P30 NS047101UC San Diego Materials Research Science and Engineering Center
6 · The paper itself

Abstract

Peptide-based coacervates are biocompatible and tunable but inherently unstable due to weak, reversible noncovalent interactions, making them vulnerable to stress from pH and temperature. This is especially difficult for coacervates used in commercial products with low-temperature storage or lyophilization. We engineered lyophilization-tolerant nanocoacervates by incorporating aromatic tyrosine residues into oligopeptide [(YR)

Indexed as

OligopeptidesPeptidesPolyphenolsTyrosineFreeze DryingHydrogen BondingHydrogen-Ion ConcentrationTanninsTemperatureOligopeptidesPeptidesPolyphenolsTanninsTyrosinearomatic interactionslyophilizationpeptide coacervatespolyphenol networkstability

Identifiers

PMID41287479
PMCPMC13110416

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.