ArticleAndrology2026
Polyglycolic Acid Polymer Versus Porcine Small Intestine Submucosa Graft After Plaque Incision in Peyronie's Disease: A Comparative Study.
Article in Andrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeyronie's disease (PD) with severe penile curvature often requires surgical correction through plaque incision and grafting (PIG).
objectivesTo compare surgical outcomes between polyglycolic acid polymer grafts and porcine small intestinal submucosa (SIS) grafts in patients undergoing PIG for PD. MATERIALS AND
methodsThis retrospective cohort study included patients with PD who underwent PIG using either Gore Bio-A (BioA group, n = 20) or SIS grafts (Cook Biotech, West Lafayette, IN, USA; SIS group, n = 21). The primary outcome was the incidence of postoperative erectile dysfunction (ED). Secondary outcomes included the degree of penile curvature correction, sensory disturbances, patient satisfaction, and surgical complications.
resultsThe median age was 61 years in the BioA group and 57 years in the SIS group (p = 0.381). The BioA group exhibited a significantly higher rate of refractory ED compared to the SIS group (p = 0.006). No significant differences were observed between groups in terms of penile straightening, sensory alterations, postoperative complications, or the need for penile prosthesis implantation. Patient satisfaction was significantly higher in the SIS group (p = 0.015). DISCUSSION: This study is the first to directly compare Gore Bio-A and SIS grafts in PIG surgery for PD. Despite similar safety profiles and high curvature correction rates in both groups, erectile function outcomes were significantly better in the SIS group. Patient-reported satisfaction also favored SIS. Although associated with higher rates of ED, Gore Bio-A may still represent a viable option in selected cases, particularly when PIG is performed in conjunction with penile prosthesis implantation. Limitations include the retrospective, non-randomized design, and small sample size.
conclusionIn this cohort, the SIS graft was associated with better postoperative outcomes than the BioA graft, with lower rates of refractory ED and higher patient satisfaction following PIG for PD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.