Isothermal recombinase polymerase amplification based diagnostics for female genital schistosomiasis and human papillomavirus: a review of combined molecular diagnostic opportunities.

Lucy Isabelle Smith, Sanjeev Krishna, Helen Kelly, Amaya Bustinduy, Bonnie Webster

Abstract readReview

In one paragraph

Review in Parasitology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Preface to parasites of the genital tract: short- and long-term consequences.Parasitology · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lucy Isabelle SmithClinical Research Department, London School of Hygiene and Tropical Medicine, London, UK.ORCID https://orcid.org/0009-0002-3985-9990

Sanjeev KrishnaDepartment of Medicine, City St George's University of London, London, UK.

Helen KellyClinical Research Department, London School of Hygiene and Tropical Medicine, London, UK.

Amaya BustinduyClinical Research Department, London School of Hygiene and Tropical Medicine, London, UK.ORCID https://orcid.org/0000-0001-6131-4159

Bonnie WebsterDepartment of Science, Natural History Museum, London, UK.ORCID https://orcid.org/0000-0003-0930-9314

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Women in sub-Saharan Africa face complex, multifaceted challenges to their health, including a high burden of infectious diseases aggravated by socioeconomic factors. Parasitic and sexually transmitted infections both cause significant morbidity and mortality. Co-infections compound these effects, leading to high rates of chronic illness and making diagnosis and treatment challenging. There are no integrated approaches for the detection of female genital schistosomiasis (FGS), a gynaecological condition caused by

Indexed as

Molecular Diagnostic TechniquesNucleic Acid Amplification TechniquesPapillomaviridaePapillomavirus InfectionsSchistosomiasis haematobiaAfrica South of the SaharaAnimalsCoinfectionFemaleHuman Papillomavirus VirusesHumansSchistosoma haematobiumfemale genital schistosomiasisHPVisothermalsmolecular diagnosticsrecombinase polymerase amplificationSchistosomasexual health

Identifiers

PMID41287386

DOI10.1017/S0031182025101248

PMCPMC13124305

What OpenQuestion holds

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LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.