ArticleAnnals of medicine2025
The German LAKE-score reliably predicts urinary and dietary potential renal acid load: a three-armed translational study.
Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Boron Intake and 24-hour Urinary Excretion in Long-term Omnivores, Vegetarians and Vegans: a Cross-sectional Study.Biological trace element research · 2026Article
- The Potential Renal Acid Load of Edible Marine and Land Snails.NPJ science of food · 2026Article
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Authors and funding
7 authors.
Funding
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Abstract
backgroundEvidence supports kidney injury from a high potential renal acid load (PRAL). Existing predictive equations to estimate the PRAL have important limitations and require either a 24-h urine collection or the estimation of an individual's nutrient intake. The LAKE (load of acid to kidney evaluation) score offers a more pragmatic solution; however, the score has never been translated into the German language. MATERIALS AND
methodsWe translated the LAKE score into German, and validated it in a three-armed study in a healthy population comprised of omnivores, lacto-ovo-vegetarians and vegans. Using weighed food diaries, we estimated the participants' dietary PRAL (PRAL
resultsThe study sample comprised 89 individuals. Results suggested a strong correlation between the long version of the LAKE score and the
conclusionThe German version of the LAKE score is a rapid, inexpensive and feasible tool for an initial PRAL evaluation in a clinical context, characterized by a good validity and reliability. Results suggest that the German LAKE score could be suitable as an estimate for an individual's PRAL, and could also guide clinicians to make dietary recommendations and monitor PRAL-relevant changes in individual patients.
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