Evidence map›Paper›PMID 41287106›Full record

ArticleInternational journal of retina and vitreous2025

Global perspectives of ophthalmologists on artificial intelligence adoption in clinical practice.

Lorenzo Ferro Desideri, Yousif Subhi, Janice Roth, Enrico Bernardi, Gustavo Barreto Melo, Edmund Tsui, Adrian T Fung, Nicola Sagurski, Charles Wykoff, Hasenin Al-Khersan and 7 more

Abstract read
In one paragraph

Article in International journal of retina and vitreous, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Lorenzo Ferro DesideriDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern, CH-3010, Switzerland. lorenzoferrodes@gmail.com.
Yousif SubhiDepartment of Ophthalmology, Rigshospitalet, Glostrup, Denmark.
Janice RothDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern, CH-3010, Switzerland.
Enrico BernardiDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern, CH-3010, Switzerland.
Gustavo Barreto MeloDepartment of Ophthalmology and Visual Sciences, Federal University of Sao Paulo, Sao Paulo, Brazil.
Edmund TsuiStein Eye Institute, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Adrian T FungFaculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Nicola SagurskiDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern, CH-3010, Switzerland.
Charles WykoffRetina Consultants of Texas, Retina Consultants of America, Houston, TX, USA.
Hasenin Al-KhersanRetina Consultants of Texas, Retina Consultants of America, Houston, TX, USA.
Jose Carlo M ArtiagaDepartment of Clinical Epidemiology, College of Medicine, University of the Philippines Manila, Manila City, Philippines.
Ogugua OkonkwoDepartment of Ophthalmology, Eye Foundation Hospital and Eye Foundation Retinal Institute, Lagos, Lagos State, Nigeria.
Hung-Da ChouDepartment of Ophthalmology, Chang Gung Memorial Hospital, Linkou Medical Center, Taiwan and College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Pierre-Henry GabrielleOphthalmology Department, Dijon University Hospital, Dijon, France.
Jay ChhablaniOphthalmology, University of Pittsburgh, Pittsburgh, PA, USA.
Martin ZinkernagelDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern, CH-3010, Switzerland.
Rodrigo AnguitaDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern, CH-3010, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArtificial intelligence (AI) is rapidly expanding in ophthalmology, yet its adoption in daily practice remains limited. Understanding clinicians’ perspectives is essential to address barriers and guide targeted education.

methodsWe conducted a cross-sectional international survey of licensed ophthalmologists from 45 countries across all continents between October 2024 and February 2025. The questionnaire evaluated AI familiarity and use as primary outcomes, as well as perceived clinical impact, ethical concerns, and training preferences of participants. Descriptive and comparative analyses were conducted across world region, practice type, and professional seniority.

resultsA total of 622 ophthalmologists completed the survey. While 69.5% anticipated a moderate-to-very potential for AI to improve clinical outcomes, only 7.2% reported regular use. Familiarity with AI was significantly higher among academic clinicians (p = 0.0011), whereas 49.6% reported no knowledge of specific AI tools. Key barriers included lack of training (20.5%), implementation costs (16.5%), and reliability concerns (12.9%). Ethical issues most frequently cited were algorithmic bias (44.2%), liability (36.7%), and reduced physician–patient interaction (19.9%). Ophthalmologists with > 20 years of experience were more likely to support AI adoption (OR 1.5). Interest in AI education was high (75.1%), with a preference for online and structured formats and calls for earlier integration into medical curricula.

conclusionsDespite broad recognition of AI’s potential in ophthalmology, adoption remains low and familiarity limited. Lack of training, cost, and ethical concerns represent key barriers. Tailored, accessible education and institutional support are urgently needed to facilitate safe and effective AI integration into clinical practice.

Indexed as

AI in ophthalmologyAI trainingArtificial intelligenceEthical concerns

Identifiers

PMID41287106
PMCPMC12751991

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.