Evidence map›Paper›PMID 41286958›Full record

ArticleJournal of ovarian research2025

Bushen Zhuluan Decoction alleviates diminished ovarian reserve by regulating the m

Huizhen Liang, Pingfang Tang, Qing Du, Xin Chen, Ling Wang

Abstract read
In one paragraph

Article in Journal of ovarian research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Huizhen LiangDepartment of Clinic of Integrated Traditionalï¿¿Western Medicine, The Maternal and Child Health Hospital of Hunan Province, No. 53 Xiangchun Road, Wangluyuan Street, Kaifu District, Changsha City, Hunan Province, P.R. China. lianghuizhen0107@163.com.
Pingfang TangDepartment of Second School of Clinical Medicine, Hunan University of Chinese Medicine, Changsha City, Hunan Province, P.R. China.
Qing DuDepartment of Second School of Clinical Medicine, Hunan University of Chinese Medicine, Changsha City, Hunan Province, P.R. China.
Xin ChenDepartment of Second School of Clinical Medicine, Hunan University of Chinese Medicine, Changsha City, Hunan Province, P.R. China.
Ling WangDepartment of Clinic of Integrated Traditionalï¿¿Western Medicine, The Maternal and Child Health Hospital of Hunan Province, No. 53 Xiangchun Road, Wangluyuan Street, Kaifu District, Changsha City, Hunan Province, P.R. China.

Funding

Key Laboratory of Integrated Traditional Chinese and Western Medicine for Maternal and Child Health (Hunan Maternal and Child Health Hospital) (Hunan Central Medicine Letter (2022) No. 93)
6 · The paper itself

Abstract

Diminished ovarian reserve (DOR) is an important pathogenic factor contributing to infertility among women of childbearing age. Bushen Zhuluan Decoction (BZD) has been observed to enhance ovarian function. The aim of this study was to investigate the pharmacological effects of BZD on DOR and elucidate its underlying mechanism of action. A DOR rat model was established by gastric gavage with Tripterygium wilfordii polyglycosides (TWPs). Ovarian pathological alterations were evaluated using HE staining. The serum FSH, LH, E2 and AMH levels were measured by ELISA; the mRNA and protein expression levels were determined by qRT‒PCR, western blot analysis and immunohistochemistry; and a specific kit was used to assess the m

Indexed as

Drugs, Chinese HerbalOvarian ReserveAnimalsFemaleGranulosa CellsHumansMethylationMethyltransferasesRatsRats, Sprague-DawleyDrugs, Chinese HerbalMethyltransferasesBushen zhuluan decoctionDiminished ovarian reserveM6AMETTL3PLGF

Identifiers

PMID41286958
PMCPMC12751762

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.