Evidence map›Paper›PMID 41286953›Full record

Observational studyReproductive health2025

Reproductive health characteristics among women living in severe poverty in urban Haiti.

Wheytnie Alexandre, Anju Ogyu, Rodney Sufra, Lily D Yan, Marie M Deschamps, Catherine Bennett, Jean William Pape, Laura C Alonso, Vanessa Rouzier, Margaret L McNairy

Abstract readObservational Study
In one paragraph

Observational study in Reproductive health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wheytnie AlexandreCenter for Global Health, Weill Cornell Medicine, NYC, NY, USA. wha4002@med.cornell.edu.
Anju OgyuCenter for Global Health, Weill Cornell Medicine, NYC, NY, USA.
Rodney SufraHaitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), Port-au-Prince, Haiti.
Lily D YanCenter for Global Health, Weill Cornell Medicine, NYC, NY, USA.
Marie M DeschampsHaitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), Port-au-Prince, Haiti.
Catherine BennettCenter for Global Health, Weill Cornell Medicine, NYC, NY, USA.
Jean William PapeHaitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), Port-au-Prince, Haiti.
Laura C AlonsoDivision of Endocrinology, Diabetes & Metabolism, Weill Cornell Medicine, NYC, NY, USA.
Vanessa RouzierCenter for Global Health, Weill Cornell Medicine, NYC, NY, USA.
Margaret L McNairyCenter for Global Health, Weill Cornell Medicine, NYC, NY, USA.

Funding

Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep DisordersR01HL143788 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Margaret Leighton McNairy · 2018 to 2026
$8.9M
Research Training in Endocrinology and MetabolismT32DK131957 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI Laura C Alonso · 2023 to 2026
$1.1M
Environmental Lead Pollution and Heart Failure in HaitiK23HL177149 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Lily Du Yan · 2025 to 2026
$423k
NHLBI NIH HHS K23 HL177149NHLBI NIH HHS R01 HL143788NIDDK NIH HHS T32 DK131957NIH HHS R01HL143788
6 · The paper itself

Abstract

backgroundData on women’s reproductive health in settings facing extreme poverty are limited. We describe the reproductive health characteristics across the life course of women living in urban Port-au-Prince, Haiti, and identify factors associated with adverse pregnancy outcomes (APO).

methodsData were sourced from the Haiti Cardiovascular Disease Cohort Study, a population-based observational study in Port-au-Prince. This analysis includes all women who completed a reproductive health questionnaire, which included self-reported age of menarche, menopause, infertility, menstruation abnormalities, and APO, defined as a history of pregnancy loss, preterm births, and pregnancy complications. We performed univariable and multivariable log-binomial regression to identify factors associated with APO.

resultsAmong 1746 women in the parent cohort, 1,163 (66.6%) women reported reproductive health data. The median age was 43 years (IQR 31–55). The median age at menarche was 14 years (IQR 12–16). A downward trend in the age of menarche was observed over time: women born from 1930 to 1970 reported a median age of 15 years, compared to 13 years among women born from 1990 to 2012 (p < 0.001). 11% (11.0%; n = 130) of the participants reported a history of infertility. The median age of reported menopause was 48 years (IQR, 44–50; n = 540), with approximately 37.4% (n = 203) experiencing menopause before the age of 45. Among 1007 women with ≥ one pregnancy, 61.7% (n = 623) experienced an APO, and 20.3% (n = 206) reported two or more APO. The most common APO was pregnancy loss (n = 515, 51.0%), pregnancy complications (n = 244, 24.0%), and preterm births (n = 132, 13.0%). Factors associated with a history of APO included hypertension, body mass index > 25 kg/m2, higher education, and a moderate perceived stress score.

conclusionAmong women living in extreme poverty in Haiti, we found a high prevalence of adverse reproductive health outcomes, namely APO, and a temporal trend of a decreasing age of menarche across time. Adverse reproductive health outcomes have been associated with increased chronic disease, and additional research is needed to establish if these factors are associated with increased cardiometabolic disease in extremely poor settings to identify targets for future prevention and treatment.

Indexed as

PovertyPregnancy ComplicationsPregnancy OutcomeReproductive HealthAdolescentAdultFemaleHaitiHumansMenarcheMenopauseMiddle AgedPregnancyUrban PopulationAdverse pregnancy outcomesHaitiMiscarriagePregnancy complicationsPregnancy lossReproductive healthStillbirths

Identifiers

PMID41286953
PMCPMC12751971

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.