Evidence map›Paper›PMID 41286939›Full record

ArticleTrials2025

Evaluating primary suicide prevention in adolescents with risk factors (ESPAIR): study protocol for a cluster-randomized controlled trial.

Stéphanie Baggio, Eleanor Bailey, Anne Edan, Patrick Heller, Carole Kapp, Nadejda Lambert, Laurent Michaud, Adrian P Mundt, Neslie Nsingi, Sophia Perez and 8 more

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06551038 (Evaluating Primary Suicide Prevention in Adolescents With Risk Factors), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06551038 narecruitingnot on this map

Evaluating Primary Suicide Prevention in Adolescents With Risk Factors

TypeinterventionalSponsorStephanie BaggioRan2025 to 2028Enrolled240ConditionsSuicide PreventionArmsPrimary suicide prevention intervention, Art-based control intervention
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Stéphanie BaggioInstitute of Psychology, University of Lausanne, Lausanne, Switzerland. stephanie.baggio@unil.ch.ORCID http://orcid.org/0000-0002-5347-5937
Eleanor BaileyOrygen Centre for Youth Mental Health, University of Melbourne, Melbourne, Australia.
Anne EdanChild and Adolescent Psychiatric Clinical Service, Geneva University Hospitals, Geneva, Switzerland.
Patrick HellerPsychiatry Department, Geneva University Hospitals, Geneva, Switzerland.
Carole KappDivision of Child and Adolescent Psychiatry, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Nadejda LambertAssociation Stop Suicide, Geneva, Switzerland.
Laurent MichaudPsychiatric Liaison Service, Lausanne University Hospital, Lausanne, Switzerland.
Adrian P MundtCentro de Investigación Biomédica, Facultad de Medicina, Universidad Diego Portales, Santiago, Chile.
Neslie NsingiInstitute of Psychology, University of Lausanne, Lausanne, Switzerland.
Sophia PerezAssociation Stop Suicide, Geneva, Switzerland.
Santiago PeregalliChild and Adolescent Psychiatric Clinical Service, Geneva University Hospitals, Geneva, Switzerland.
Camille PiguetPsychiatry Department, Geneva University Hospitals, Geneva, Switzerland.
Caroline PiotrowskiCollege of Community & Global Health, University of Manitoba, Winnipeg, Canada.
Yekaterina PrutyanovaInstitute of Psychology, University of Lausanne, Lausanne, Switzerland.
Mathias RumleyPrimary and Secondary School Center Lavaux, Puidoux, Switzerland.
Marlène SapinSwiss Center of Expertise in Social Sciences (FORS) & Interdisciplinary Center of Life Course Research (LIVES), University of Lausanne, Lausanne, Switzerland.
Sébastien UrbenDivision of Child and Adolescent Psychiatry, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Katia IglesiasSchool of Health Sciences, HES-SO University of Applied Sciences and Arts of Western Switzerland, Fribourg, Switzerland.

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 10000272
6 · The paper itself

Abstract

backgroundSuicide is the leading cause of death among young people. Because it is preventable, suicide prevention has become a critical public health priority worldwide. Current evidence suggests that primary suicide prevention interventions are effective in promoting suicide awareness and reducing suicidal thoughts among adolescents. However, scarce research has been conducted in vulnerable populations who may be at increased risk of suicidal behaviour. This project aims to test the effectiveness of a primary suicide prevention intervention on suicide awareness, knowledge of suicide and local resources, suicidal thoughts, psychological distress, and safety.

methodsThis study is an open-label, multi-centre, superiority, cluster-randomized controlled trial with two parallel arms (randomization 1:1 in at least 8 study sites) of a primary suicide prevention intervention based on psychoeducation versus an art-based control intervention. Four groups of youth aged 14-25 with high suicide risk will be recruited (in total, n = 240), including those (1) detained in juvenile detention centres, (2) disconnected from school, (3) in treatment for psychiatric disorders, (4) belonging to a sexual or gender diversity, (5) affected by chronic conditions, and (6) with relational/familial problems. Participants will be randomly assigned to the suicide prevention or control intervention. The primary outcome is suicide awareness measured on a validated scale. Secondary outcomes include knowledge of suicide, knowledge of local resources, suicidal behaviour, psychological distress, access to primary suicide prevention, and safety. Measures will be collected at baseline, at 1-week, and 3-month follow-ups. Analyses will be conducted as intention-to-treat using mixed-effects models. DISCUSSION: We expect that a brief primary suicide prevention intervention (psychoeducation) will be effective and safe in vulnerable adolescents.

trial registrationClinicalTrials.gov NCT06551038. Registered on August 13, 2024.

Indexed as

Adolescent BehaviorPrimary PreventionSuicide PreventionAdolescentAdultEquivalence Trials as TopicFemaleHealth Knowledge, Attitudes, PracticeHumansMaleMulticenter Studies as TopicRandomized Controlled Trials as TopicRisk FactorsSuicidal IdeationSuicideYoung AdultChronic conditionFoster careLGBTQIA+Mental healthPrisonPsychoeducationSchool disengagementUniversal prevention

Identifiers

PMID41286939
PMCPMC12642238

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.