Evidence map›Paper›PMID 41286902›Full record

ReviewThrombosis journal2025

Cancer-Associated Thrombosis (CAT); mechanisms and treatment options.

Fahad S Alshehri, Abdurahman Alloghbi, Abdulrahman Alshalani, Hassan Abu Sabah, Claire S Whyte

Abstract readReview
In one paragraph

Review in Thrombosis journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Emerging Insights of Management of Venous Thromboembolism in Patients With Cancer.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fahad S AlshehriKing Faisal Medical City for Southern Region, Pathology and Clinical Laboratory Medicine Department, Haematology Division, Abha, Saudi Arabia. fsalshehrii@kfmcity.med.sa.
Abdurahman AlloghbiDepartment of Oncology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Abdulrahman AlshalaniDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Hassan Abu SabahKing Faisal Medical City for Southern Region, Pathology and Clinical Laboratory Medicine Department, Haematology Division, Abha, Saudi Arabia.
Claire S WhyteAberdeen Cardiovascular & Diabetes Centre, School of Medicine, Medical Science and Nutrition, Institute of Medical Science, University of Aberdeen, Aberdeen, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer-associated thrombosis (CAT), especially venous thromboembolism (VTE), is the second highest cause of mortality in cancer patients, following the cancer itself. Notably, among patients with thrombosis, cancer is the most common underlying cause of death, highlighting the strong interrelationship between these conditions. Tumour cells primarily promote a prothrombotic environment through activation of procoagulant properties of the host cells. Additionally, chemotherapy, radiotherapy and hormone treatments may amplify the thrombotic risk in cancer patients. Consequently, both arterial thromboses, including myocardial infarction (MI) and ischemic stroke (IS), and venous thrombosis, such as deep vein thrombosis (DVT) and pulmonary embolism (PE), are significantly more prevalent among patients with malignancies. This review will discuss the association between cancer and thrombosis, illustrate the most common risk factors and discuss the direct and indirect molecular mechanisms involved.

Indexed as

Arterial thrombosisCancerPlateletsTumour cellsVenous thrombosis

Identifiers

PMID41286902
PMCPMC12642358

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.