Evidence map›Paper›PMID 41286900›Full record

ArticleBMC public health2025

Plant-based diets especially healthy ones are negatively associated with depression: a cross-sectional study.

Bao Zhang, Meiling Li, Xiude Li

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bao Zhang *Department of Clinical Nutrition, the First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei, Anhui, 230022, China.
Meiling Li *Department of Nutrition and Food Hygiene, School of Public Health, Anhui Medical University, Hefei, Anhui, 230032, China.
Xiude LiDepartment of Clinical Nutrition, the First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei, Anhui, 230022, China. xiudeli@foxmail.com.

Funding

National Key Research and Development Program of China 2020YFC2006502
6 · The paper itself

Abstract

backgroundDiet was a potentially modifiable factor in the prevention of depression. We aimed to investigate associations of an overall plant-based diet index (PDI), a healthful PDI (hPDI), and an unhealthful PDI (uPDI) with the prevalence of depression. We hypothesized that plant-based diets especially the hPDI may be associated with lower depression, whereas uPDI would increase the depression.

methodsThis is a cross-sectional study using data from the US National Health and Nutrition Examination Survey 2005-2018. Diet was assessed by 24-hour recalls. Depression was measured using the Patient Health Questionnaire-9 (PHQ-9). Odds ratios (ORs) and percentage changes (%) were calculated by logistic regression and linear regression, respectively.

resultsAmong the 31,622 participants aged 20 years or older, the age-standardized prevalence of major depression (PHQ-9 score ≥ 10) was 8.8% (n = 2,744). The overall PDI was not associated with odds of depression (OR comparing extreme quintiles 0.84, 95% confidence interval [CI]: 0.66-1.07; p

conclusionsPlant-based diets, especially when they are enriched with healthier plant foods, may be beneficial for primary prevention of depression. However, plant-based diets that emphasize less healthy plant foods are associated with higher depression levels among US adults.

Indexed as

DepressionDiet, HealthyDiet, Plant-BasedAdultAgedCross-Sectional StudiesFemaleHumansLogistic ModelsMaleMiddle AgedNutrition SurveysOdds RatioPatient Health QuestionnairePrevalenceUnited StatesDepressionHealthful plant-based dietPatient health questionnaire-9Plant-based dietUnhealthful plant-based diet

Identifiers

PMID41286900
PMCPMC12764046

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.