Evidence map›Paper›PMID 41286853›Full record

ArticleJournal of inflammation (London, England)2025

Butyrate ameliorates ulcerative colitis through targeting STING-dependent ER stress signaling and limiting CD4

Tengfei Xiao, Jingjing Kang, Chuanxiang Zhao, Rong Zhu, Mingzhong Sun, Yungang Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of inflammation (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tengfei Xiao *Department of Clinical Laboratory, Yancheng Third People's Hospital, Affiliated Hospital 6 of Nantong University, Yancheng, Jiangsu, 224000, China.
Jingjing Kang *Department of Clinical Laboratory, Yancheng First Hospital, Affiliated Hospital of Nanjing University Medical School, The First People's Hospital of Yancheng, Yancheng, Jiangsu, 224000, China.
Chuanxiang ZhaoLaboratory Medicine, Institute of Medical Genetics and Reproductive Immunity, School of Medical Science, Jiangsu College of Nursing, Huai'an, Jiangsu, 223001, China.
Rong ZhuDepartment of Clinical Laboratory, Yancheng Third People's Hospital, Affiliated Hospital 6 of Nantong University, Yancheng, Jiangsu, 224000, China.
Mingzhong SunDepartment of Clinical Laboratory, Yancheng Third People's Hospital, Affiliated Hospital 6 of Nantong University, Yancheng, Jiangsu, 224000, China. syjykzr@163.com.
Yungang WangDepartment of Clinical Laboratory, Yancheng Third People's Hospital, Affiliated Hospital 6 of Nantong University, Yancheng, Jiangsu, 224000, China. wyg301647@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the role of butyrate in regulating STING-induced endoplasmic reticulum stress (ERS) and CD4

Indexed as

ButyrateCD4+TRM T cellscGSA-STING pathwayERSUlcerative colitis

Identifiers

PMID41286853
PMCPMC12642100

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.