Trial reportBMC medicine2025
Economic evaluation of a multi-component obesity prevention intervention in Chinese primary schools.
Trial report in BMC medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03665857 (A School-based Multicomponent Intervention Study for Preventing Excessive Weight Gain Among Primary School Students), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A School-based Multicomponent Intervention Study for Preventing Excessive Weight Gain Among Primary School Students
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Authors and funding
7 authors.
Funding
Abstract
backgroundHealth economic evaluations of childhood obesity interventions are critical for determining the economic feasibility, sustainability, and scalability, thereby informing their policy relevance. This study conducted a comprehensive economic evaluation of a multi-component, App-assisted obesity prevention intervention-compared with usual care-to assess its value for widespread implementation.
methodsThe Diet, Exercise, and Cardiovascular Health-Children (DECIDE-Children) intervention was a cluster randomized clinical trial involving 24 schools across three socioeconomically distinct regions in China, targeting children aged 8 to 10 years. Schools were randomly assigned (1:1) to either the intervention group or the control group (usual health education). The intervention included school, family, and student components supported by a mobile application for health education, behavior monitoring, weight management, and feedback. A societal perspective was adopted for the economic evaluation. Total costs included direct financial expenditures (e.g., materials, equipment) and labor costs. Incremental cost-effectiveness ratios (ICERs) were calculated for primary obesity-related outcome measure. Using an obesity progression model, we estimated the number of adult obesity cases prevented up to age 65, quality-adjusted life years (QALYs) gained, incremental cost-utility ratio (ICUR), cost-benefit ratio (CBR), and net benefits.
resultsThe total cost of implementing the 1-year intervention was 13,769.74 USD, averaging 19.53 USD per student in the intervention group. Compared with usual care, the ICERs were as follows: 42.46 USD (95% CI 29.15 to 78.12) per 1-unit reduction in BMI; 11.49 USD (95% CI 7.81 to 21.70) per 0.1-unit reduction in BMI Z-score; 18.60 USD (95% CI 10.67 to 69.75) per 1% reduction in body fat percentage; 11.98 USD (95% CI 6.93 to 45.42) per 1-cm reduction in waist circumference. The ICUR was 4644.42 USD per QALY gained, and the CBR was 0.84. National implementation was projected to yield 419,040 QALYs gained and USD 1.86 billion in net benefits. Sensitivity analyses supported the robustness of findings.
conclusionsThe DECIDE-Children intervention is a cost-effective strategy for childhood obesity prevention, providing significant public health and economic benefits. Its integration of school, family, and digital components offers a scalable, sustainable model for addressing childhood obesity in China and other developing settings.
trial registrationClinicalTrials.gov Identifier NCT03665857.
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