Evidence map›Paper›PMID 41286694›Full record

ArticleBMC medical research methodology2025

Use of quasi-experimental studies to evaluate causal effects of public health interventions in Portugal: a scoping review.

A Leite, I Kislaya, A Machado, P Aguiar, B Nunes, C Matias Dias

Abstract readScoping Review
In one paragraph

Article in BMC medical research methodology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A LeiteDepartment of Epidemiology, Instituto Nacional de Saúde Doutor Ricardo Jorge, Lisbon, 1649-016, Portugal. andreia.leite@insa.min-saude.pt.
I KislayaNOVA National School of Public Health, Public Health Research Centre, Comprehensive Health Research Center, CHRC, REAL, CCAL, NOVA University Lisbon, Lisbon, 1600-407, Portugal.
A MachadoDepartment of Epidemiology, Instituto Nacional de Saúde Doutor Ricardo Jorge, Lisbon, 1649-016, Portugal.
P AguiarNOVA National School of Public Health, Public Health Research Centre, Comprehensive Health Research Center, CHRC, REAL, CCAL, NOVA University Lisbon, Lisbon, 1600-407, Portugal.
B NunesNOVA National School of Public Health, Public Health Research Centre, Comprehensive Health Research Center, CHRC, REAL, CCAL, NOVA University Lisbon, Lisbon, 1600-407, Portugal.
C Matias DiasDepartment of Epidemiology, Instituto Nacional de Saúde Doutor Ricardo Jorge, Lisbon, 1649-016, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundQuasi-experimental designs are a valid option to assess causal effects of public health interventions when randomized studies are unfeasible, but not widely used in Portugal. We identified and reviewed characteristics of studies employing quasi-experimental designs to evaluate causal effects of public health interventions in Portugal.

methodsPubMed, Scopus, Web of Science and CINHAL were searched, alongside grey literature, reference mining and contact of authors of eligible studies. We extracted information on the intervention assessed, study design, outcomes assessed, statistical analysis and reporting guidelines.

resultsWe identified 1143 studies; 25 were eligible. Studies assessed interventions in various areas, mainly healthcare services (28.0%), drugs/tobacco consumption policy (20.0%), and COVID-19 related restrictions (20.0%). Studies employed interrupted time series (56.0%) and difference-in-differences designs (44.0%). Analyses utilised regression-based models, namely linear (48.0%), negative binominal (20.0%) and logistic (12.0%). Studies analysed 53 outcomes, with two outcomes per study on average. No reporting guidelines were mentioned.

conclusionsThere is a limited number of studies using quasi-experimental designs to estimate the causal effects of public health interventions in Portugal, mainly interrupted time series and difference-in-differences. Training in this area might promote the adequate use and dissemination of quasi-experimental studies.

Indexed as

COVID-19Public HealthResearch DesignHumansInterrupted Time Series AnalysisPortugalSARS-CoV-2Causal effectsPublic healthQuasi-experimental studies

Identifiers

PMID41286694
PMCPMC12642283

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.