Evidence map›Paper›PMID 41286550›Full record

ArticleMagnetic resonance in medicine2026

Feasibility Study for Dual Phase Free Breathing 3D bSSFP MRA With Preserved Eddy-Current Tolerance With Adaptive k-Space Lengths (PETAL) Acquisition.

Tassia Ribeiro Salles Moura, Dingheng Mai, Emma Wexler, Lydia P Lewis, Wajeh Abuirmaileh, Angel Houston, Kathy Kohut, Eric Roselli, Deborah Kwon, David Chen and 2 more

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tassia Ribeiro Salles MouraCardiovascular Innovation Research Center, Heart Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.ORCID https://orcid.org/0009-0005-1847-4049
Dingheng MaiCardiovascular Innovation Research Center, Heart Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0002-5055-3231
Emma WexlerCardiovascular Innovation Research Center, Heart Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Lydia P LewisCleveland Clinic Lerner College of Medicine at Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Wajeh AbuirmailehCardiovascular Innovation Research Center, Heart Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Angel HoustonCardiovascular Innovation Research Center, Heart Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Kathy KohutCardiovascular Innovation Research Center, Heart Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Eric RoselliHeart Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Deborah KwonCardiovascular Innovation Research Center, Heart Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
David ChenCardiovascular Innovation Research Center, Heart Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Danielle KaraCardiovascular Innovation Research Center, Heart Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0001-8369-798X
Christopher T NguyenCardiovascular Innovation Research Center, Heart Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0003-1475-2329

Funding

Serial evaluation of cardioprotective effects of exercise training in heart failure using cardiac diffusion tensor MRIR01HL151704 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI NGUYEN, CHRISTOPHER T · 2020 to 2024
$3.4M
Microstructural Response of the Myocardium to Mechanical LoadR01HL159010 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI MEKKAOUI, CHOUKRI, NGUYEN, CHRISTOPHER T · 2021 to 2024
$3.2M
Improving Phenotypic Classification and Prediction of Treatment Outcomes in Patients with Non-ischemic Cardiomyopathy and Functional Mitral RegurgitationR01HL170090 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI DEBORAH KWON · 2023 to 2026
$3.1M
Modeling, measurement and prediction of cardiac magneto-stimulation thresholdsR01EB033853 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Bastien Guerin, Christopher T Nguyen · 2023 to 2026
$2.4M
Demonstrating the Feasibility of Democratized Push-Button Autonomous Cardiac MRI exam in Community Family Health Centers (AutoCMR for FHC)R01HL180504 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI David Chen, Christopher T Nguyen · 2025 to 2026
$1.5M
NHLBI NIH HHS R01 HL151704NHLBI NIH HHS R01 HL159010NHLBI NIH HHS R01 HL170090NHLBI NIH HHS R01 HL180504NIBIB NIH HHS R01 EB033853NIH HHS R01 EB033853NIH HHS R01 HL151704NIH HHS R01 HL159010NIH HHS R01 HL180504
6 · The paper itself

Abstract

purposeTo demonstrate the feasibility of a novel dual-phase self-navigated, free-breathing balanced steady-state free-precession whole-heart MRA acquisition for aortic annulus size measurement using a Cartesian trajectory that mitigates eddy-current artifacts by minimizing k-space jumps between consecutive readouts with predictable scan times.

methodsThe proposed method uses a trajectory with Preserved Eddy-current Tolerance with Adaptive k-space Lengths (PETAL) that enables the acquisition of multiple navigators per heartbeat to address respiratory motion throughout a 330-510 ms acquisition window across different cardiac phases. Imaging was performed in 15 healthy volunteers on a 3 T MR system using a sequence compiled in Pulseq. Images were reconstructed in systole and diastole. Aortic annulus perimeter and area were measured for both cardiac phases. A clinical MRA and a breath-held 2D bSSFP cine planned at the valve plane were used to statistically compare metrics in diastole and systole, respectively.

resultsIn diastole, the PETAL sequence yielded a high correlation with the clinical reference for aortic annulus area (

conclusionThe proposed approach enables dual-phase, contrast-free, free-breathing acquisition of isotropic 3D whole-heart images in predictable 10 min scan times for aortic size measurements in systole and diastole.

Indexed as

Aortic ValveHeartImage Processing, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance AngiographyAdultAlgorithmsArtifactsDiastoleFeasibility StudiesFemaleHealthy VolunteersHumansImage Interpretation, Computer-AssistedMaleRespiration3D whole‐heart MRAbSSFPeddy‐currentfree‐breathingself‐gatingtrajectory

Identifiers

PMID41286550
PMCPMC12850613

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.