Evidence map›Paper›PMID 41286544›Full record

ArticleSpine deformity2026

Exploring the indications, failures, and treatment of complications after a C2 to pelvis fusion.

Nathan J Lee, Fthimnir M Hassan, Ted Shi, Anastasia Ferraro, Matthew Cooney, Chun Wai Hung, Steven G Roth, Justin K Scheer, Zeeshan M Sardar, Joseph M Lombardi and 2 more

Abstract read
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In one paragraph

Article in Spine deformity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nathan J LeeDepartment of Orthopaedic Surgery, Midwest Orthopaedics at Rush, Chicago, IL, USA.
Fthimnir M HassanDepartment of Orthopaedic Surgery, Columbia University Medical Center, The Och Spine Hospital at New York-Presbyterian, New York, NY, USA. fh2444@cumc.columbia.edu.ORCID http://orcid.org/0000-0003-3928-8972
Ted ShiDepartment of Orthopaedic Surgery, Columbia University Medical Center, The Och Spine Hospital at New York-Presbyterian, New York, NY, USA.
Anastasia FerraroDepartment of Orthopaedic Surgery, Columbia University Medical Center, The Och Spine Hospital at New York-Presbyterian, New York, NY, USA.
Matthew CooneyDepartment of Orthopaedic Surgery, Columbia University Medical Center, The Och Spine Hospital at New York-Presbyterian, New York, NY, USA.
Chun Wai HungDepartment of Orthopaedic Surgery, Columbia University Medical Center, The Och Spine Hospital at New York-Presbyterian, New York, NY, USA.
Steven G RothDepartment of Orthopaedic Surgery, Columbia University Medical Center, The Och Spine Hospital at New York-Presbyterian, New York, NY, USA.
Justin K ScheerDepartment of Orthopaedic Surgery, Columbia University Medical Center, The Och Spine Hospital at New York-Presbyterian, New York, NY, USA.
Zeeshan M SardarDepartment of Orthopaedic Surgery, Columbia University Medical Center, The Och Spine Hospital at New York-Presbyterian, New York, NY, USA.
Joseph M LombardiDepartment of Orthopaedic Surgery, Columbia University Medical Center, The Och Spine Hospital at New York-Presbyterian, New York, NY, USA.
Lawrence G LenkeDepartment of Orthopaedic Surgery, Columbia University Medical Center, The Och Spine Hospital at New York-Presbyterian, New York, NY, USA.
Ronald A LehmanDepartment of Orthopaedic Surgery, Columbia University Medical Center, The Och Spine Hospital at New York-Presbyterian, New York, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo better elucidate the C2-related complications and treatments among ASD patients with C2-ilium fusions.

methodsA single-center series of patients who underwent a posterior spinal instrumented fusion (PSIF) from C2-ilium were included. Patient demographics, medical history, diagnosis, operative procedures, and complications were analyzed.

results37 C2-ilium patients were included with a mean follow-up of 2.8 years, age of 56 ± 19 years, 57% were female, and 38% had osteoporosis/osteopenia. Most patients had a prior fusion surgery 81% (N = 30), which commonly included upper thoracic to sacrum (N = 15) and cervical-thoracic (N = 5) fusions. The most common surgical indications included PJK/F (N = 12), chin-on-chest deformity (N = 5), and pseudarthrosis (N = 5). The surgical complication rate was 46% (17/37), the revision surgery rate was 38% (14/37), and 3 patients required multiple revision surgeries. Reoperations commonly addressed C2-related fractures (N = 6), wound complications (N = 5), and pseudarthrosis unrelated to C2 (N = 4). For those with C2 issues, surgery included either extension of fusion to Occiput (N = 2) and C1 (N = 4) or revision C2 (N = 2). Four patients with radiographic C2 issues were treated non-operatively in a hard collar after appearing stable on repeat imaging.

conclusionThis is the largest series of C2-ilium reconstructions with a mean follow-up of 2 years. The most common surgical indication was PJK/F, followed by chin-on-chest deformity and pseudarthrosis. The surgical complication and revision rate was 46% and 38%, respectively. The most common reason for revision surgery was C2-related fractures and screw loosening, with 43% being extended to C1 or the occiput. Long constructs from C2-ilium carry a high complication rate and require frequent follow-up to assess for long-term issues.

Indexed as

Cervical VertebraePostoperative ComplicationsSpinal FusionAdultAgedFemaleFollow-Up StudiesHumansIliumMaleMiddle AgedPseudarthrosisReoperationRetrospective StudiesTreatment FailureAdult spinal deformityC2 to pelvisComplicationsPatient reported outcomesPostoperative outcomesReoperationsSatisfaction

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.