ReviewArchives of pharmacal research2025
Diterpenoids from the genus Croton and their biological activities.
Review in Archives of pharmacal research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Diterpenoids in medicinal plants: structure, distribution, biological activities, biosynthesis, and bioengineering prospects.Frontiers in plant science · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The genus Croton, a member of the Euphorbiaceae family, comprises nearly 1300 species globally, predominantly inhabiting tropical and subtropical regions. Certain species of Croton are renowned for their significant medicinal properties. Diterpenoids, as the principal bioactive constituents of this genus, exhibit a diverse array of biological activities. From 2013 to 2025, a total of 545 newly identified diterpenoids featuring 34 distinct skeletal types, predominantly labdane, clerodane, tigliane, and crotofolane structures, were isolated from 45 Croton species, including several novel frameworks. According to available literature, Croton diterpenoids demonstrate notable anti-inflammatory and anti-tumor properties, with clerodane and tigliane variants showing particularly promising results. Additionally, antimicrobial, anti-proliferative, anti-angiogenic, neuroprotective, insecticidal, and anti-liver fibrotic activities have been reported for various Croton diterpenoids. This review consolidates information on the distribution, chemical structures, potential biosynthetic pathways and biological activities of diterpenoids isolated from Croton species during the specified period.
Indexed as
Identifiers
41286537What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.